[1]余海兵,赵杰,廖家权.银杏活脑胶囊对老年缺血性脑卒中恢复期患者轻度认知功能的影响[J].西部中医药,2025,38(11):126-129.[doi:10.12174/j.issn.2096-9600.2025.11.22]
　YU Haibing,ZHAO Jie,LIAO Jiaquan.Effects of Ginkgo Brain-activating Capsules on Mild Cognitive Impairment in Senile Patients with Ischemic Stroke during Convalescence[J].Western Journal of Traditional Chinese Medicine,2025,38(11):126-129.[doi:10.12174/j.issn.2096-9600.2025.11.22]
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银杏活脑胶囊对老年缺血性脑卒中恢复期患者轻度认知功能的影响()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年11期
页码:
126-129
栏目:
衷中参西
出版日期:
2025-11-15

文章信息/Info

Title:
Effects of Ginkgo Brain-activating Capsules on Mild Cognitive Impairment in Senile Patients with Ischemic Stroke during Convalescence
作者:
余海兵1, 赵杰2, 廖家权1
1.恩施土家族苗族自治州中心医院，湖北 恩施 445400
2.恩施州优抚医院，湖北 恩施 445400
Author(s):
YU Haibing1, ZHAO Jie2, LIAO Jiaquan1
1.The Central Hospital of Enshi Tujia and Miao Autonomous Perfecture/Enshi Clinical College of Wuhan University, Enshi 445400, China
2.Enshi Tujia and Miao Autonomous Perfecture Veterans Hospital, Enshi 445400, China
关键词:
脑卒中; 认知障碍; 银杏活脑胶囊; 生活能力; 椎动脉; 大脑中动脉
Keywords:
stroke; cognitive impairment; ginkgo brain-activating capsules; living ability; vertebral artery; middle cerebral artery
分类号:
R287
DOI:
10.12174/j.issn.2096-9600.2025.11.22
文献标志码:
B
摘要:
目的观察银杏活脑胶囊对老年缺血性脑卒中（ischemic stroke，IS）恢复期患者轻度认知功能障碍（mild cognitive impairment，MCI）的影响。 方法将老年IS恢复期伴MCI患者62例，采用随机数字表法分为对照组与观察组，每组31例。两组患者均接受常规个体化干预方案；对照组加用尼莫地平治疗，观察组在对照组用药基础上口服银杏活脑胶囊。两组疗程均为2个月。比较两组临床疗效、MCI改善情况（以简易智能量表评分衡量）、日常生活活动能力（以Barthel指数评分衡量）、脑血流动力学相关指标（椎动脉及大脑中动脉阻力指数）及不良反应发生情况。 结果连续治疗2个月后，观察组总有效率［93.55％（29/31）］高于对照组［67.74％（21/31）］（P<0.05）；两组患者简易智能量表评分、Barthel指数评分均较治疗前升高，且观察组升高幅度更明显（P＜0.05）；两组患者椎动脉、大脑中动脉阻力指数均较治疗前降低，观察组降低幅度更明显（P＜0.05）。两组患者均未发生明显不良反应。 结论银杏活脑胶囊治疗老年IS恢复期伴MCI患者的疗效确切，可有效改善患者的日常生活活动能力及脑血流动力学指标。
Abstract:
ObjectiveTo observe the effects of ginkgo brain-activating capsules on mild cognitive impair-ment (MCI) in senile patients with IS during convalescence. MethodsAll 62 senile patients with IS during convalescence and MCI were collected, and allocated to the control group and the observation group using random number table method with 31 cases in each. Both groups adopted conventional individualized intervention plan; the control group was treated with nimodipine, and the observation group took ginkgo brain-activating capsules orally on the foundation of the therapy of the control group. The course was two months. To compare curative effects, the improvements of MCI (measured with MMSE scores), activity of daily living (ADL, measured with Barthel index scores), the indexes related to cerebral hemodynamics (vertebral artery and middle cerebral artery resistance index), and the incidence of adverse reactions between the two groups. ResultsAfter two months of ongoing treatment, total effective rate of the observation group was [93.55%(29/31)], higher than [67.74%(21/31)] of the control group (P<0.05); MMSE scores and BI scales of the two groups were elevated than these before the treatment, and increase of the observation group was more evident (P<0.05); vertebral artery and middle cerebral artery RI of the two groups were lower than before the treatment, the decrease of the observation group was more noticeable (P<0.05). No obvious adverse reaction happened in the two groups. ConclusionGinkgo brain-activating capsules exhibit significant clinical efficacy for senile IS during convalescence and MCI, and it could effectively improve ADL and the indexes related to cerebral hemodynamics.

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备注/Memo

备注/Memo:
余海兵（1995—），男，主管治疗师。研究方向：现代临床康复。
更新日期/Last Update: 2025-11-15