[1]唐琪,刘新,张道雨,等.新疆地区类风湿关节炎合并慢性病贫血患者中医证候因子分析及疾病活动相关性研究[J].西部中医药,2026,39(05):50-54.[doi:10.12174/j.issn.2096-9600.2026.05.12]
　TANG Qi,LIU Xin,ZHANG Daoyu,et al.Factor Analysis of TCM Syndromes and Correlation with Disease Activity in Patients with Rheumatoid Arthritis Complicated by Anemia of Chronic Disease in the Xinjiang Region[J].Western Journal of Traditional Chinese Medicine,2026,39(05):50-54.[doi:10.12174/j.issn.2096-9600.2026.05.12]
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新疆地区类风湿关节炎合并慢性病贫血患者中医证候因子分析及疾病活动相关性研究()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年05期
页码:
50-54
栏目:
调查分析
出版日期:
2026-05-15

文章信息/Info

Title:
Factor Analysis of TCM Syndromes and Correlation with Disease Activity in Patients with Rheumatoid Arthritis Complicated by Anemia of Chronic Disease in the Xinjiang Region
作者:
唐琪, 刘新, 张道雨, 薛萌萌, 刘永丰, 欧阳文柏, 张贺超
新疆医科大学中医学院，新疆 乌鲁木齐 830000
Author(s):
TANG Qi, LIU Xin, ZHANG Daoyu, XUE Mengmeng, LIU Yongfeng, OUYANG Wenbai, ZHANG Hechao
TCM College of Xinjiang Medical University, Urumqi 830000, China
关键词:
类风湿关节炎; 贫血; 中医证候; 因子分析; 相关性分析
Keywords:
rheumatoid arthritis; anemia; TCM syndromes; factor analysis; correlation analysis
分类号:
R255.82
DOI:
10.12174/j.issn.2096-9600.2026.05.12
文献标志码:
A
摘要:
目的分析新疆地区类风湿关节炎（rheumatoid arthritis，RA）合并慢性病贫血（anemia of chronic disease，ACD）患者的中医证候，并分析证候与疾病活动指标的相关性。 方法运用因子分析中主成分分析法，旋转方法用最大方差法，相关性分析采用Spearman秩相关分析。 结果研究病例共209例，分析得出中医证候共5类，分别为寒热错杂兼肾虚气血不足证、痰瘀痹阻兼气血亏虚证、风寒痹阻兼气血亏少证、湿热瘀阻兼脾气虚证、气血两虚兼湿阻证。寒热错杂兼肾虚气血不足证与红细胞沉降率（erythrocyte sedimentation rate，ESR）、C反应蛋白（C-reactive protein，CRP）、28个关节疾病活动度评分（disease activity score 28，DAS28评分）呈正相关；痰瘀痹阻兼气血亏虚证与年龄呈正相关；风寒痹阻兼气血亏少证与年龄呈负相关；湿热瘀阻兼脾气虚证、气血两虚兼湿阻证均与DAS28评分呈负相关。 结论通过因子分析法得出新疆地区RA合并ACD患者的中医证候可分为5类，证候与部分实验室指标存在一定相关性。
Abstract:
ObjectiveTo analyze TCM syndromes in patients with rheumatoid arthritis (RA) complicated by anemia of chronic disease (ACD) in the Xinjiang region, and to investigate the correlation between these syndromes and disease activity indicators. MethodsPrincipal component analysis (PCA) was used as the factor extraction method, with varimax rotation applied for factor rotation. Spearman’s rank correlation analysis was employed for correlation analysis. ResultsA total of 209 cases were included in the study. Based on factor analysis, five TCM syndrome types were identified: (1) cold-heat complex pattern complicated by kidney deficiency and Qi-blood deficiency; (2) phlegm-stasis obstruction pattern complicated by Qi-blood deficiency; (3) wind-cold obstruction pattern complicated by Qi-blood deficiency; (4) damp-heat stasis obstruction pattern complicated by spleen-Qi deficiency; and (5) dual deficiency of Qi and blood pattern complicated by dampness obstruction. The cold-heat complex with kidney deficiency and Qi-blood deficiency pattern was positively correlated with erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and the disease activity score 28 (DAS28). The phlegm-stasis obstruction with Qi-blood deficiency pattern was positively correlated with age. The wind-cold obstruction with Qi-blood deficiency pattern was negatively correlated with age. Both the damp-heat stasis obstruction with spleen-Qi deficiency pattern and the dual deficiency of Qi and blood with dampness obstruction pattern were negatively correlated with the DAS28 score. ConclusionUsing factor analysis, TCM syndromes in patients with RA complicated by ACD in the Xinjiang region can be classified into five types. These syndromes show certain correlations with some laboratory indicators.

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备注/Memo

备注/Memo:
国家自然科学基金（81860834）；国家级一流本科专业中医学专业建设点；“十四五”自治区高等学校重点学科中医学。唐琪（1995—），女，硕士学位。研究方向：中医内科学（类风湿关节炎）临床研究。
更新日期/Last Update: 2026-05-15