[1]周柯,吴金玉,陶钰,等.中药的线粒体保护作用及其在慢性肾脏病中的应用研究进展[J].西部中医药,2026,39(06):118-121.[doi:10.12174/j.issn.2096-9600.2026.06.22]
 ZHOU Ke,WU Jinyu,TAO Yu,et al.Advances in the Study of Mitochondrial Protection by Traditional Chinese Medicine and Its Role in Chronic Kidney Disease[J].Western Journal of Traditional Chinese Medicine,2026,39(06):118-121.[doi:10.12174/j.issn.2096-9600.2026.06.22]
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中药的线粒体保护作用及其在慢性肾脏病中的应用研究进展()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年06期
页码:
118-121
栏目:
研究进展
出版日期:
2026-06-08

文章信息/Info

Title:
Advances in the Study of Mitochondrial Protection by Traditional Chinese Medicine and Its Role in Chronic Kidney Disease
作者:
周柯1, 吴金玉2, 陶钰1, 黄诗棋1
1.广西中医药大学,广西 南宁 530001
2.广西中医药大学第一附属医院,广西 南宁 530023
Author(s):
ZHOU Ke1, WU Jinyu2, TAO Yu1, HUANG Shiqi1
1.Guangxi University of Chinese Medicine, Nanning 530001, China
2.The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China
关键词:
慢性肾脏病线粒体中药研究进展
Keywords:
chronic renal diseasemitochondriatraditional Chinese medicineadvances
分类号:
R256.5
DOI:
10.12174/j.issn.2096-9600.2026.06.22
文献标志码:
A
摘要:
从单味中药及活性成分、中成药、中药复方三个层面综述中药通过调控线粒体自噬、生物合成及凋亡相关通路等改善线粒体功能、减轻肾脏损伤的研究进展,指出具有线粒体保护作用的中药,大多具有补气益气功效,说明补气益气类中药或可用于慢性肾脏病的治疗。但目前研究多以动物实验为主,需进一步开展相关临床试验,进一步验证药物的临床有效性。
Abstract:
This article reviews the research progress on how traditional Chinese medicine (TCM) improves mitochondrial function and alleviates kidney injury by regulating mitophagy, biosynthesis, and apoptosis-related pathways, the review is conducted from three levels: single herbs and their active components, Chinese patent medicines, and TCM formulas. It is pointed out that most TCMs with mitochondrial protective effects possess the function of tonifying Qi, suggesting that Qi-tonifying TCMs may be applicable for the treatment of chronic kidney disease(KD). Nevertheless, most of the existing research is limited to animal studies, and further clinical trials are required to confirm the clinical effectiveness of these agents.

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备注/Memo

备注/Memo:
国家自然科学基金(81960866)。周柯(1997—),女,硕士学位,医师。研究方向:中医药防治肾脏病及风湿病。
更新日期/Last Update: 2026-06-15