[1]康东,王红妹,薛刚.小承气合黄芪建中汤对老年术后早期炎性肠梗阻患者胃肠功能的影响[J].西部中医药,2026,39(08):158-162.[doi:10.12174/j.issn.2096-9600.2026.08.29]
　KANG Dong,WANG Hongmei,XUE Gang.Effect of Xiao Chengqi Decoction Combined with Huangqi Jianzhong Decoction on Gastrointestinal Function in Elderly Patients with Early Postoperative Inflammatory Ileus[J].Western Journal of Traditional Chinese Medicine,2026,39(08):158-162.[doi:10.12174/j.issn.2096-9600.2026.08.29]
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小承气合黄芪建中汤对老年术后早期炎性肠梗阻患者胃肠功能的影响()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年08期
页码:
158-162
栏目:
临床研究
出版日期:
2026-07-29

文章信息/Info

Title:
Effect of Xiao Chengqi Decoction Combined with Huangqi Jianzhong Decoction on Gastrointestinal Function in Elderly Patients with Early Postoperative Inflammatory Ileus
作者:
康东, 王红妹, 薛刚
如皋市中医院普外科，江苏 如皋 226500
Author(s):
KANG Dong, WANG Hongmei, XUE Gang
Department of General Surgery, Rugao Hospital of Traditional Chinese Medicine, Rugao 226500, China
关键词:
肠梗阻; 炎性; 小承气合黄芪建中汤; 胃肠功能; 老年人
Keywords:
Ileus;  inflammatory; Decoction combined with Decoction; gastrointestinal function; the elderly
分类号:
R256.3
DOI:
10.12174/j.issn.2096-9600.2026.08.29
文献标志码:
B
摘要:
目的探讨小承气合黄芪建中汤对老年术后早期炎性肠梗阻患者胃肠功能的影响。 方法采用前瞻性研究方法，选取老年术后早期炎性肠梗阻患者60例，随机分为对照组与研究组，每组30例。对照组接受术后常规西医治疗，研究组在常规西医治疗基础上联合小承气合黄芪建中汤治疗。观察两组证候疗效，术后恢复指标（肠鸣音恢复时间、肛门排气时间、首次排便时间、首次下床活动时间及住院时间）、中医症状评分，胃肠激素［胃泌素（gastrin，GAS）、胃动素（motilin，MOT）］水平，炎症因子［降钙素原（procalcitonin，PCT）、超敏C反应蛋白（high-sensitivity C-reactive protein，hs-CRP）、白细胞介素6（interleukin-6，IL-6）］水平，氧化应激指标［8-羟基脱氧鸟苷（8-hydroxy-2’-deoxyguanosine，8-OHdG）、丙二醛（malondialdehyde，MDA）、超氧化物歧化酶（superoxide dismutase，SOD）］水平。 结果研究组证候疗效［96.67%（29/30）］高于对照组［76.67%（23/30）］（P＜0.05）。研究组术后各项恢复指标值及中医症状评分均低于对照组（P＜0.05）；PCT、hs-CRP、IL-6、8-OHdG及MDA水平均低于对照组（P＜0.05）；GAS、MOT、SOD水平均高于对照组（P＜0.05）。 结论小承气合黄芪建中汤能改善老年术后早期炎性肠梗阻患者的胃肠功能，抑制机体炎症反应和过氧化反应，调节胃肠激素分泌，提高临床疗效。
Abstract:
ObjectiveTo investigate the effect of Xiao Chengqi Decoction combined with Huangqi Jianzhong Decoction on gastrointestinal function in elderly patients with early postoperative inflammatory ileus. MethodsA prospective study was conducted, involving 60 elderly patients with early postoperative inflammatory ileus, who were randomly divided into a control group and a study group, with 30 patients in each group. The control group received routine postoperative Western medical treatment, while the study group received Xiao Chengqi Decoction combined with Huangqi Jianzhong Decoction in addition to the routine Western medical treatment. The following parameters were observed and compared between the two groups: treatment response rate; postoperative recovery indicators (including recovery time of bowel sounds, time to first flatus, time to first defecation, time to first ambulation, and length of hospital stay); TCM syndrome scores; levels of gastrointestinal hormones [gastrin (GAS), motilin (MOT)]; levels of inflammatory factors [procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6)]; and levels of oxidative stress markers [8-hydroxy-2’-deoxyguanosine (8-OHdG), malondialdehyde (MDA), superoxide dismutase (SOD)]. ResultsThe total effective rate in the study group [96.67% (29/30)] was higher than that in the control group [76.67% (23/30)] (P<0.05). All postoperative recovery indicators and TCM syndrome scores in the study group were lower than those in the control group (P<0.05). The levels of PCT, hs-CRP, IL-6, 8-OHdG, and MDA in the study group were lower than those in the control group (P<0.05), while the levels of GAS, MOT, and SOD were higher than those in the control group (P<0.05). Conclusion Xiao Chengqi Decoction combined with Huangqi Jianzhong Decoction significantly improves gastrointestinal function, suppresses inflammatory and oxidative stress responses, regulates gastrointestinal hormone levels, and increases clinical efficacy in elderly patients with early postoperative inflammatory ileus.

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备注/Memo

备注/Memo:
江苏省中医药科技发展计划项目（MS2023119）。康东（1987—），男，主治医师。研究方向：外科疾病的诊断及治疗。
更新日期/Last Update: 2026-08-15