[1]陈晋玉,雷瑗琳,王南丁.中医药干预NLRP3炎症小体治疗动脉粥样硬化的研究进展[J].西部中医药,2024,37(04):112-115.[doi:10.12174/j.issn.2096-9600.2024.04.22]
　CHEN Jinyu,LEI Yuanlin,WANG Nanding.Research Progress of TCM Intervention of NLRP3 Inflammasome in the Treatment of Atherosclerosis[J].Western Journal of Traditional Chinese Medicine,2024,37(04):112-115.[doi:10.12174/j.issn.2096-9600.2024.04.22]
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中医药干预NLRP3炎症小体治疗动脉粥样硬化的研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年04期
页码:
112-115
栏目:
研究进展
出版日期:
2024-04-15

文章信息/Info

Title:
Research Progress of TCM Intervention of NLRP3 Inflammasome in the Treatment of Atherosclerosis
作者:
陈晋玉1, 雷瑗琳2, 王南丁1,2
1.陕西中医药大学，陕西 咸阳 712046
2.西安市中医医院,陕西 西安 710021
Author(s):
CHEN Jinyu1, LEI Yuanlin2, WANG Nanding1,2
1.Shaanxi University of Chinese Medicine, Xianyang 712046, China
2.Xi'an Hospital of Traditional Chinese Medicine, Xi'an 710021, China
关键词:
动脉粥样硬化; 核苷酸结合寡聚化结构域样受体蛋白3; 炎症小体; 中医药
Keywords:
atherosclerosis; nucleotide-binding oligomerized structural domain-like receptor protein 3; inflammasome; Chinese medicine
分类号:
R543.1+2
DOI:
10.12174/j.issn.2096-9600.2024.04.22
文献标志码:
A
摘要:
从中医药干预核苷酸结合寡聚化结构域样受体蛋白3（nucleotide-binding oligomerization domain-like receptor protein 3，NLRP3）炎症小体入手，阐述中医药发挥抗炎的作用机理，认为NLRP3炎症小体参与的炎症反应贯穿动脉粥样硬化（atherosclerosis，AS）发展的全过程，其中清热药、活血药及补虚药在治疗AS中具有极大优势，为中医药治疗AS疾病提供新思路。
Abstract:
Based on the intervention of traditional Chinese medicine on nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome, the paper discussed the anti-inflammatory mechanism of traditional Chinese medicine. It is believed that inflammatory response involved in NLRP3 runs through the entire process of the development of atherosclerosis (AS). Among them, heat-clearing drugs, blood-activating drugs and deficiency-tonifying drugs have great advantages in the treatment of AS, providing new ideas for traditional Chinese medicine treatment of AS.

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备注/Memo

备注/Memo:
陈晋玉（1995—），男，硕士学位，医师。研究方向：中医心病的临床与基础研究。国家自然科学基金项目（81503444）；陕西省自然科学基础研究计划（2020JQ-966）；西安市科协青年人才托举计划（095920201330）。
更新日期/Last Update: 2024-04-15