新玉贞散治疗儿童多发性抽动症临床观察-《西部中医药》

文章信息/Info

Title:: Clinical Observation on XinYuZhenSan in Treating Children with Tourette Syndrome

Author(s):: CHEN Jiangyu, ZHANG Chunhua; Tianshui Municipality the First People′s Hospital, Tianshui 741000, China

摘要:: 目的：观察新玉贞散治疗儿童多发性抽动症的临床疗效及不良反应。方法：将儿科门诊就诊的80例儿童多发性抽动症患儿随机分为治疗组与对照组各40例。治疗组采用新玉贞散治疗，对照组采用盐酸硫必利治疗，治疗2月后停药，随访6月，观察2组临床疗效及不良反应发生率。结果：治疗组总有效率为87.5%，对照组为62.5%，2组比较差异有统计学意义(P＜0.05)，且治疗组不良反应明显低于对照组(P＜0.05)。结论：新玉贞散治疗儿童多发性抽动症疗效显著，且不良反应发生率低。

Abstract:: Objective: To observe clinical effects and adverse reaction of XinYuZhenSan in treating children with tourette syndrome. Method: Eighty patients were randomized into the treatment group and the control group. The treatment group took XinYuZhenSan and the control group tiapride hydrochloride, both groups were treated for two months and followed for six months, clinical effects and adverse reaction of both groups were observed. Result: Total effective rate of the treatment group was 87.5%, higher than 62.5% of the control group, the difference between both groups had statistical meaning (P＜0.05), adverse reaction of the treatment group was remarkably lower than that of the control group(P＜0.05). Conclusion: XinYuZhenSan is effective in treating tourette syndrome with minor adverse reaction.