[1]贾国龙,邓强,张雪霞.参附注射液对老年膝关节置换术围术期循环稳定性的影响[J].西部中医药,2014,27(06):99-100.
　JIA Guolong,DENG Qiang,ZHANG Xuexia.Effects of ShenFu Injection on Hemodynamics of Senile Patients with Knee Replacement in Perioperative Period[J].Western Journal of Traditional Chinese Medicine,2014,27(06):99-100.
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参附注射液对老年膝关节置换术围术期循环稳定性的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年06期
页码:
99-100
栏目:
出版日期:
2014-06-15

文章信息/Info

Title:
Effects of ShenFu Injection on Hemodynamics of Senile Patients with Knee Replacement in Perioperative Period
文章编号:
1004-6852(2014)06-0099-02
作者:
贾国龙，邓强,张雪霞
甘肃省中医院，甘肃 兰州730050
Author(s):
JIA Guolong, DENG Qiang, ZHANG Xuexia
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
参附注射液; 膝关节置换术; 血流动力学; 心功能
Keywords:
ShenFu injection;  knee replacement;  hemodynamics;  heart function
分类号:
R687.4
摘要:
目的：观察参附注射液对老年患者膝关节置换术围术期循环稳定性的影响。方法:选择60例行膝关节置换术老年患者随机分为参附组和对照组各30例。参附组在麻醉前将1 mL/kg的参附注射液溶于200 mL的生理盐水中，术前20分钟内输完，对照组则使用同等量的生理盐水代替。2组均采用腰麻-硬膜外联合麻醉。观察麻醉前(T1)、麻醉后(T2)、胫骨扩髓后(T3)、放骨水泥后(T4)、术毕松止血带后(T5)5个时间点的收缩压(SBP)、舒张压(DBP)、HR、SpO2、中心静脉压(CVP)。结果：参附组T2、T3及T5时间点时CVP升高(P＜0.05),T3、T4及T5时间点时SBP、DBP降低、HR升高(P＜0.01)。T2时间点2组CVP比较差异有统计学意义(P＜0.05);T3、T4及T5时间点2组SBP、DBP及HR比较差异均有统计学意义(P＜0.05)。结论：参附注射液用于老年人膝关节置换术可明显增强心肌泵功能，保持血流动力学平稳。
Abstract:
Objective: To explore the effects of ShenFu injection on hemodynamics of senile patients with knee replacement in perioperative period. Methods: Sixty patients were randomly allocated to ShenFu group and the control group. Before anaesthesia, ShenFu group accepted intravenous injection of ShenFu injection, 1mL/kg, which was dissolved in physiological saline, 200mL, finished in 20 minutes before the surgery, and the control group with the same amount of physiological saline. Both groups received combined spinal and epidural anesthesia. SBP, DBP, HR, SpO2 and CVP were observed at five time points including before (T1) and after anesthesia (T2), after tibia reaming (T3), after placing bone cement(T4) and after releasing tourniquet when the operation was over(T5). Results: CVP was increased at T2, T3 and T5 of ShenFu group (P＜0.05), SBP and DBP were decreased but HR was raised at T3, T4 and T5 (P＜0.01). The difference showed statistical meaning at T2 between both groups (P＜0.05); the difference demonstrated statistical meaning in SBP, DBP and HR at T3, T4 and T5 between both groups (P＜0.05). Conclusion: ShenFu injection applied to senile patients with knee replacement could significantly increase myocardial pumping function and keep hemodynamics stable.

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备注/Memo

备注/Memo:
收稿日期：2013-12-10作者简介：贾国龙(1976—)，男，主治医师。研究方向：临床麻醉。
更新日期/Last Update: 2014-06-15