[1]严文有,李有成△,赵斌庆,等.僵卿金沸草散治疗咳嗽变异性哮喘疗效观察[J].西部中医药,2014,27(09):97-99.
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僵卿金沸草散治疗咳嗽变异性哮喘疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年09期
页码:
97-99
栏目:
出版日期:
2014-09-15

文章信息/Info

作者:
严文有李有成△赵斌庆王志超
武威市计划生育技术服务站,甘肃 武威 733000
关键词:
咳嗽变异性哮喘LTB4IL-4姜卿金沸草散
分类号:
R562.2
摘要:
目的:观察僵卿金沸草散治疗咳嗽变异性哮喘的临床疗效及其对血清中LTB4、IL-4表达的影响。方法:将咳嗽变异性哮喘患者60例随机分为2组各30例,治疗组口服僵卿金沸草散治疗:对照组口服孟鲁司特、酮替芬治疗。观察2组患者用药前后症状、体征变化情况并检测LTB4、IL-4的表达水平。结果:治疗组显效22例,有效6例,无效2例,总有效率93.33%,对照组显效20例,有效6例,无效4例,总有效率86.67%,治疗组临床疗效优于对照组;LTB4、IL-4 2组治疗前比较差异无统计学意义(P>0.05),治疗后组内比较差异显著(P<0.01)。结论:僵卿金沸草散治疗咳嗽变异性哮喘,可能通过抑制LTB4、IL-4的表达水平,维持Th1/Th2平衡,从而控制气道炎症,减少咳嗽变异性哮喘的发作,疗效优于孟鲁司特、酮替芬。

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备注/Memo

备注/Memo:
作者简介:严文有(1964—),男,副主任医师。研究方向:呼吸系统疾病的中西医结合治疗。△通讯作者:李有成(1964—),男,副主任医师。研究方向:呼吸系统疾病的中西医结合治疗。
更新日期/Last Update: 2014-09-15