[1]祝伟,田浩.川芎嗪联合小剂量雷公藤治疗儿童哮喘急性发作期患儿38例[J].西部中医药,2015,28(02):102-104.
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川芎嗪联合小剂量雷公藤治疗儿童哮喘急性发作期患儿38例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年02期
页码:
102-104
栏目:
出版日期:
2015-02-15

文章信息/Info

文章编号:
1004-6852(2015)02-0102-03
作者:
祝伟1田浩2
1 郑州市第一人民医院儿科, 河南 郑州 450004; 2 郑州大学第一附属医院检验科
关键词:
支气管哮喘急性发作期川芎嗪雷公藤T淋巴细胞亚群Th1/Th2细胞因子儿童
分类号:
R753.7
摘要:
目的:观察川芎嗪联合小剂量雷公藤治疗儿童哮喘急性发作期的临床疗效。方法:将80例哮喘急性发作期患者随机分为2组。对照组给予西医常规治疗,治疗组在此基础上给予川芎嗪加小剂量雷公藤治疗。观察2组临床疗效及治疗前后肺功能及CD3+、CD4+、CD8+T、γ-干扰素(IFN-γ)、白细胞介素-2(IL-2)、白细胞介素-4(IL-4)、白细胞介素-12(IL-12)水平。结果:治疗组临床疗效优于对照组,差异有统计学意义(P<0.05)。CD4+细胞、血清IL-4水平均较对照组明显下降(P<0.01),第一秒用力呼气量(FEV1)、呼气峰值流速(PEF)改善均优于对照组(P<0.05)。结论:川芎嗪加小剂量雷公藤具有缓解哮喘急性发作期患儿临床症状、改善肺功能的作用。

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备注/Memo

备注/Memo:
作者简介:祝伟(1972—),男,副主任医师。研究方向:儿科呼吸疾病的诊治。
更新日期/Last Update: 2015-02-15