[1]罗明辉,杨济源,黄河涛,等.基于关联规则和复杂系统熵聚类的腰椎管狭窄症用药规律研究[J].西部中医药,2016,29(04):89-91.
　LUO Minghui,YANG Jiyuan,HUANG Hetao,et al.Study on Medication Rules of Lumbar Spinal Stenosis Based on Association Rules of Complex System Entropy Clustering[J].Western Journal of Traditional Chinese Medicine,2016,29(04):89-91.
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基于关联规则和复杂系统熵聚类的腰椎管狭窄症用药规律研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年04期
页码:
89-91
栏目:
出版日期:
2016-04-15

文章信息/Info

Title:
Study on Medication Rules of Lumbar Spinal Stenosis Based on Association Rules of Complex System Entropy Clustering
文章编号:
1004-6852(2016)04-0089-03
作者:
罗明辉1，杨济源2，黄河涛3，刘军1△，潘建科3，谢辉3
1 广东中医药大学第二附属医院/广东省中医院，广东 广州 510120； 2 惠州市中医医院骨二科；3 广州中医药大学第二临床医学院
Author(s):
LUO Minghui1, YANG Jiyuan2, HUANG Hetao3, LIU Jun1△, PAN Jianke3, XIE Hui3
1 Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China; 2 The Second Orthopedic Department of Huizhou Municipality TCM Hospital;3 The Second Clinical Medical School of Guangzhou University of Chinese Medicine
关键词:
腰椎管狭窄症; 组方规律; 关联规则; 聚类算法
Keywords:
lumbar spinal stenosis;  prescription rules;  association rules;  entropy algorithm
分类号:
R681.5
摘要:
目的：基于中医传承辅助平台(TCMISS)软件分析腰椎管狭窄症中药处方的用药规律。方法：通过中国知网、重庆维普、万方数据库收集近5年治疗腰椎管狭窄症文献中的中药处方，分析处方中各种药物的使用频次、药物之间的关联规则、核心药物组合。结果:对筛选出的100个中药处方进行分析，确定处方中药物的使用频次，四气五味，归经，药物之间的关联规则，挖掘出16个核心组合。结论:腰椎管狭窄症常用的药物以活血化瘀药、补血药、补阳药、祛风湿散寒药、补气药、发散风寒药、祛湿药为主，治法主要是活血祛瘀、益气补血、补阳、祛风湿散寒。药物四气的分布以温、平、凉为主，五味的分布以甘、辛、苦为主。药物归经的分布以肝、肾、脾为主。当归、川芎、独活、杜仲、地龙、黄芪、赤芍、牛膝、白芍、秦艽、甘草、红花、桃仁、桑寄生是临床治疗腰椎管狭窄症常用的核心药物。
Abstract:
Objective: To analyze medication rules of herbal prescription for lumbar spinal stenosis based on the software of Traditional Chinese Medicine Inheritance Support System(TCMISS). Methods: Herbal prescriptions in the paper about treating lumbar spinal stenosis in recent five yeares were collected from CNKI, VIP and WanFang databases, to analyze the frequency of the herbs, association rule between herbs and core drug combinations in the prescription. Results: One hundred prescriptions were chosen and analyzed to ensure the frequency of herbs in the prescriptions, four properties and five tastes, the meridians, association rules between herbs, to dig out 16 core drug combinations. Conclusion: Commonly-used drugs of lumbar spinal stenosis are the ones of blood-activating and stasis-eliminating, blood-replenishing, Yang-tonifying, wind-damp expelling and cold-dispelling, Qi-tonifying, wind-cold dispersing, dampness-eliminating mainly, therapeutic methods are mainly to promote blood circulation and eliminate blood stasis, tonify Qi and replenish blood, tonify Yang, expel wind-damp and dispel cold. Four properties of the herbs are warm, neutral and cool, five tastes are sweet, acrid and bitter, and tropism meridians of the herbs are of liver, kidney and spleen. Commonly-used core drugs of treating lumbar spinal stenosis are DangGui (Angelica sinensis), ChuanXiong(Ligusticum chuanxiong Hort.), DuHuo (Radix Angelicae Pubescentis), DuZhong(Eucommia ulmoides Oliver), rainworm, HuangQi[Astragalus membranaceus(Fisch.) Bunge.], ChiShao (Radix Paeoniae Rubra), NiuXi(Achyranthes bidentata Blume.), BaiShao(Paeonia lactiflora Pall.), QinJiao (Gentiana macrophylla Pall.), GanCao (Glycyrrhiza uralensis Fisch.), HongHua (Carthamus tinctorius L.), TaoRen (Semen Persicae) and SangJiSheng (parasite scurrula).

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备注/Memo

备注/Memo:
收稿日期：2015-10-06*基金项目：广东省财政厅项目(编号［2014］157号)；广东省中医药局科研项目(编号20131161)；广东省中医院中医药科学技术研究专项(编号YK2013B2N19)。作者简介：罗明辉(1981—)，男，硕士学位，主治医师。研究方向：骨伤科疾病的中医临床诊治。△通讯作者：刘军(1966—)，男，博士后合作导师，博士研究生导师，教授，主任医师。研究方向：脊柱与关节退行性疾病。
更新日期/Last Update: 2016-04-15