[1]孙博,周其辉.七叶皂苷钠联合甘露醇治疗脑出血53例[J].西部中医药,2017,30(04):97-99.
　SUN Bo,ZHOU Qihui.Combination of Sodium Aeseinate and Mannitol in the Treatment of 53 Patients with Intracerebral Hemorrhage[J].Western Journal of Traditional Chinese Medicine,2017,30(04):97-99.
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七叶皂苷钠联合甘露醇治疗脑出血53例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年04期
页码:
97-99
栏目:
出版日期:
2017-04-15

文章信息/Info

Title:
Combination of Sodium Aeseinate and Mannitol in the Treatment of 53 Patients with Intracerebral Hemorrhage
文章编号:
1004-6852(2017)04-0097-03
作者:
孙博1，周其辉2
1 湖北科技学院，湖北 437100； 2 安徽省桐城市人民医院
Author(s):
SUN Bo1, ZHOU Qihui 2
1 Hubei Technology College, Hubei 437100, China; 2 Tongcheng People′s Hospital of Anhui Province
关键词:
脑出血; 七叶皂苷钠; 甘露醇; 神经功能缺损评分; 日常生活能力评分
Keywords:
intracerebral hemorrhage;  sodium aeseinate;  mannitol;  NIHSS scores;  BI scores
分类号:
R743.34
文献标志码:
B
摘要:
目的：观察七叶皂苷钠联合甘露醇治疗脑出血的临床疗效。方法：将106例患者根据入院顺序随机分为观察组、对照组各53例，2组均给予常规药物治疗，对照组同时采用甘露醇50 mg静脉滴注，观察组在对照组治疗的基础上采用七叶皂苷钠10 mg静脉滴注，2组均连续治疗14天，比较2组临床疗效,治疗前后神经功能缺损(NIHSS)评分、日常生活能力(BI)评分的变化情况及不良反应。结果：总有效率观察组为98.1%，对照组为79.2%，2组比较差异有统计学意义(P＜0.05)。NIHSS及BI评分治疗前后组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较，差异也有统计学意义(P＜0.05)。不良反应发生率观察组为7.5%，对照组为18.9%，2组比较差异有统计学意义(P＜0.05)。结论：甘露醇联合七叶皂苷钠治疗脑出血临床疗效显著，可较好地改善神经功能，且不良反应小。
Abstract:
Objective: To observe clinical effects of the combination of sodium aeseinate and mannitol in the treatment of intracerebral hemorrhage. Methods: All 106 patients were randomly divided into the observation group and the control group according to admission order, and 53 cases in each group. Both groups were given conventional medical treatment, and the control group was given intravenous dripping with 50mg mannitol at the same time. Based on the control group, the observation group was also given intravenous dripping with 10mg sodium aeseinate. Both groups were treated continuously for 14 days. Clinical effects, National Institutes of Health Stroke Scale (NIHSS) scores, Barthel Index (BI) scores changes and adverse reactions of two groups were compared before and after treatment. Results: The total effective rate of the observation group was 98.1%, and that of the control group was 79.2%, the differences between two groups were significant (P＜0.05). Compared the NIHSS scores and BI scores within groups before and after treatment, the differences were statistically significant (P＜0.05); compared within groups after treatment, the differences were also statistically significant (P＜0.05). Adverse reactions incidence of the observation group was 7.5%, and that of the control group was 18.9%, the differences between two groups were significant (P＜0.05). Conclusion: Combination of mannitol and sodium aeseinate has significant clinical effect in the treatment of intracerebral hemorrhage, and it can better improve neurological functions with less adverse reactions.

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备注/Memo

备注/Memo:
收稿日期：2016-08-20 作者简介：孙博(1993—)，男，学生。研究方向：心脑血管疾病的临床诊治。
更新日期/Last Update: 2017-04-15