[1]张靓,赵雷,孙芳园,等.升降散治疗瘀毒内阻型脓毒症的临床研究[J].西部中医药,2017,30(12):45-47.
　ZHANG Liang,ZHAO Lei,SUN Fangyuan,et al.Clinical Study of ShengJiang Powder in the Treatment of Sepsis of Stasis-Toxin Internal Obstruction Pattern[J].Western Journal of Traditional Chinese Medicine,2017,30(12):45-47.
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升降散治疗瘀毒内阻型脓毒症的临床研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年12期
页码:
45-47
栏目:
出版日期:
2017-12-15

文章信息/Info

Title:
Clinical Study of ShengJiang Powder in the Treatment of Sepsis of Stasis-Toxin Internal Obstruction Pattern
文章编号:
1004-6852(2017)12-0045-03
作者:
张靓，赵雷，孙芳园，沈梦雯，吴笑阳，钱义明△
上海中医药大学附属岳阳中西医结合医院急诊医学科，上海 200437
Author(s):
ZHANG Liang, ZHAO Lei, SUN Fangyuan, SHEN Mengwen, WU Xiaoyang, QIAN Yiming△
Department of Emergency Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
关键词:
脓毒症; 风温病; 瘀毒内阻证; 炎症因子; 血小板
Keywords:
sepsis;  wind warm disease;  stasis-toxin internal obstruction pattern;  inflammatory factor;  blood platelet
分类号:
R714.62+6
文献标志码:
B
摘要:
目的：观察升降散治疗瘀毒内阻型脓毒症的临床疗效。方法：将50例患者随机分为对照组和观察组，每组各25例；对照组给予西医常规治疗，观察组在西医常规治疗的基础上加用升降散，疗程7天。观察2组治疗前后慢性健康状况评分(APACHEⅡ)、C反应蛋白(CRP)、血小板计数(PLT)、肿瘤坏死因子α(TNF-α)、中医证候积分的变化情况和临床疗效。结果：治疗后2组APACHEⅡ评分、CRP、TNF-α均降低，PLT升高，且观察组优于对照组(P＜0.05)。2组中医证候积分均降低，观察组疗效优于对照组(P＜0.05)。结论：升降散结合西医治疗脓毒症风温病瘀毒内阻证的临床疗效优于单纯西医治疗，其机制可能与降低炎症因子、减轻炎症反应，同时调节血小板有关。
Abstract:
Objective: To observe clinical effects of ShengJiang powder in treating sepsis of stasis-toxin internal obstruction pattern. Methods: All 50 patients were randomly allocated to the control group and the observation group, 25 cases each group, the control group accepted routine treatment of western medicine, and the observation group took ShengJiang powder on the foundation of the routine therapy of western medicine, the course was seven days. Clinical effects, the changes of TCM syndrome scales, TNF-α, PLT, CRP and the scales of APACHEⅡ of both groups were observed before and after treating. Results: The scales of APACHEⅡ, CRP and TNF-α of both groups lowered after treating, PLT raised, and the observation group was superior to the control group (P＜0.05).TCM syndrome scales of both groups decreased, the observation group was superior to the control group in clinical effects (P＜0.05). Conclusion: Clinical effects of ShengJiang powder combined with western medicine are superior to only western medicine in the treatment of sepsis of stasis-toxin internal obstruction pattern, and its mechanism might be related to reducing inflammatory factors, relieving inflammatory reaction and regulating blood platelet simultaneously.

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备注/Memo

备注/Memo:
收稿日期：2017-06-27 *基金项目：上海市进一步加快中医药事业发展三年行动计划(编号ZY3-JSFC-2-1042)。 作者简介：张靓(1981—)，女，主治医师。研究方向：急危重症。 △通讯作者：钱义明(1965—)，男，博士学位，主任医师。研究方向：急危重症。
更新日期/Last Update: 2017-12-15