[1]刘敏.加味四妙汤治疗宫颈HPV感染42例[J].西部中医药,2018,31(02):93-95.
　LIU Min.Modified SiMiao Decoction in Treating 42 Cases of Cervical HPV Infection[J].Western Journal of Traditional Chinese Medicine,2018,31(02):93-95.
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加味四妙汤治疗宫颈HPV感染42例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年02期
页码:
93-95
栏目:
出版日期:
2018-02-15

文章信息/Info

Title:
Modified SiMiao Decoction in Treating 42 Cases of Cervical HPV Infection
文章编号:
1004-6852(2018)02-0093-03
作者:
刘敏
南京市第二医院药剂科，江苏 南京 210003
Author(s):
LIU Min
Pharmacy Department, The Second Hospital of Nanjing, Nanjing 210003, China
关键词:
人乳头瘤病毒; 宫颈; 加味四妙汤; 重组人干扰素
Keywords:
HPV;  the cervix;  modified SiMiao decoction;  recombinant human interferon
分类号:
R711.74
文献标志码:
B
摘要:
目的：观察加味四妙汤治疗宫颈人乳头瘤病毒(HPV)感染的临床疗效。方法：将84例患者随机分为观察组、对照组各42例，2组均给予重组人干扰素a2b栓剂治疗，阴道内用，1次/d。观察组同时给予加味四妙汤内服及外阴熏洗治疗。结果：接触性出血、外阴瘙痒、带下异常、小腹疼痛、腰骶酸痛积分治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。HPV-DNA病毒载量、HPV转阴率治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。总有效率观察组为92.86%，对照组为83.33%，2组比较差异有统计学意义(P＜0.05)。副反应发生率观察组为11.90%，对照组为14.29%，2组比较差异无统计学意义(P＞0.05)。结论：加味四妙汤治疗宫颈HPV感染能够提高临床效果，改善临床症状。
Abstract:
Objective: To observe clinical effects of modified SiMiao decoction in treating cervical human papillomavirus (HPV) infection. Methods: All 84 patients were randomized into the observation group and the control group, 42 cases each group, both groups were treated with recombinant human interferon a2b suppository, putting into the vagina, once each day. The observation group accepted oral administration and vulval fumigation with modified SiMiao decoction simultanesouly. Results: The difference had statistical meaning in the comparisons of the scales of contact bleeding, pruritus vulvae, leukorrheal diseases, pain of lower abdomen, lumbosacral ache before and after treating within two groups (P＜0.05); the difference had statistical meaning in the comparisons between both groups after treating (P＜0.05). The difference showed statistical meaning in the comparison of HPV-DNA virus load and HPV negative conversion rate within two groups before and after treating (P＜0.05); there was a significant difference in the comparisons between both groups afrer the treating (P＜0.05). Total effective rate of the observation group was 92.86%, higher than 83.33% of the control group, and the difference had statistical meaning (P＜0.05). The incidence of adverse reaction of the observation group was 11.90%, lower than 14.29% of the control group, and the difference had no statistical meaning (P＞0.05). Conclusion: Modified SiMiao decoction in treating cervical HPV infection could raise clinical effects and improve clinical symptoms.

相似文献/References:

[1]赵秋菊.宫颈旁注射联合妇炎康复片治疗盆腔炎性疾病后遗症40例[J].西部中医药,2017,30(08):135.
　ZHAO Qiuju.Treating 40 Patients with Sequelae of PID by Paracervical Injection Combined with FuYanKangFu Tablets[J].Western Journal of Traditional Chinese Medicine,2017,30(02):135.
[2]刘敏.加味四妙汤辅助治疗宫颈HPV感染疗效观察[J].西部中医药,2019,32(01):98.
　LIU Min.Observation on Clinical Effects of Modified SiMiao Decoction as Adjunctive Therapy in Treating Cervical HPV Infection[J].Western Journal of Traditional Chinese Medicine,2019,32(02):98.

备注/Memo

备注/Memo:
收稿日期：2017-08-15 作者简介：刘敏(1973—)，女，副主任药师。研究方向：医院药学。
更新日期/Last Update: 2018-02-15