[1]周美英,李瑞丰.苍附导痰汤联合炔雌醇环丙孕酮治疗多囊卵巢综合征临床观察[J].西部中医药,2018,31(12):107-110.
　ZHOU Meiying,LI Ruifeng.Clinical Observation on CangFu DaoTan Decoction Joined with Ethinylestradiol and Cyproterone Acetate Tablets in Treating Polycystic Ovarian Syndrome[J].Western Journal of Traditional Chinese Medicine,2018,31(12):107-110.
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苍附导痰汤联合炔雌醇环丙孕酮治疗多囊卵巢综合征临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年12期
页码:
107-110
栏目:
出版日期:
2018-12-15

文章信息/Info

Title:
Clinical Observation on CangFu DaoTan Decoction Joined with Ethinylestradiol and Cyproterone Acetate Tablets in Treating Polycystic Ovarian Syndrome
文章编号:
1004-6852(2018)12-0107-04
作者:
周美英，李瑞丰
甘肃省人民医院妇产科，甘肃 兰州 730000
Author(s):
ZHOU Meiying, LI Ruifeng
Department of Obstetrics and Gynecology, Gansu Provincial Hospital, Lanzhou 730000, China
关键词:
多囊卵巢综合征; 苍附导痰汤; 炔雌醇环丙孕酮; 高雄血症
Keywords:
polycystic ovarian syndrome;  CangFu DaoTan decoctiong;  ethinylestradiol and cyproterone acetate tablets;  hyperandrogenism
分类号:
R588.6
摘要:
目的：观察苍附导痰汤联合炔雌醇环丙孕酮治疗多囊卵巢综合征的临床疗效。方法：将120例患者随机分为观察组和对照组，每组60例。2组患者均给予炔雌醇环丙孕酮片及二甲双胍缓释片治疗，观察组在此基础上给予苍附导痰汤口服，1剂/d。观察2组患者临床疗效，体质指数，Ferriman-Ganllway毛发评分，血清学指标，卵巢超声检测结果，中医证候积分及治疗中出现的不良反应。结果：临床症状，体质指数，Ferriman-Ganllway毛发评分2组患者治疗后均有改善，观察组优于对照组，差异有统计学意义(P＜0.05)。月经异常、胸腹痞满、神疲嗜睡、面目虚浮及多毛痤疮等中医证候2组均有所改善，观察组优于对照组差异有统计学意义(P＜0.05)。血清学指标及B超监测指标，观察组优于对照组(P＜0.05)。不良反应发生率2组比较，差异无统计学意义(P＞0.05)。结论：苍附导痰汤联合炔雌醇环丙孕酮治疗多囊卵巢综合征临床疗效显著。
Abstract:
Objective：To observe clinical effects of CangFu DaoTan decoction combined with ethinylestradiol and cyproterone acetate tablets in treating polycystic ovarian syndrome (PCOS). Methods: All 120 patients were randomized into the observation group and the control group, 60 cases each group. Both groups were treated by ethinylestradiol and cyproterone acetate tablets and metformin sustained-release tablets, the observation group took CangFu DaoTan decoction orally based on the therapy of Western medicine, one dose each day. Clinical effects, constitutional indexes, Ferriman-Ganllway hair scores, serological index, ovarian ultrasound results, TCM syndrome scores and adverse reaction during therapeutic course in both groups were observed. Results: Clinical symptoms, constitutional indexes and Ferriman-Ganllway hair scores improved, the observation group was superior to the control group and the difference was found in the comparison(P＜0.05); TCM syndromes including abnormal menstruation, pleural and abdominal distension, drowsiness, facial edema, hairy and acne improved, the observation group was superior to the control group and the difference was found in the amparison(P＜0.05); the observation group was superior to the control group in serological index and ovarian ultrasound results(P＜0.05); The difference had no statistical meaning in the comparisons of adverse reaction between both groups after treating(P＞0.05). Conclusion: CangFu DaoTan decoctioncombined with ethinylestradiol and cyproterone acetate tablets are effective in treating PCOS.

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备注/Memo

备注/Memo:
收稿日期：2018-03-15 *基金项目：国家自然科学基金(编号81260387)；省自然科学基金(编号1208RJZ109)。 作者简介：周美英(1972—)，女，副主任医师。研究方向：妇科肿瘤及妇科内分泌疾病的诊治。
更新日期/Last Update: 2018-12-15