[1]魏灵祯.同型半胱氨酸/超敏C反应蛋白与心脑血管疾病的关系[J].西部中医药,2018,31(10):150-152.
　WEI Lingzhen.Study on the Correlation between Homocysteine/High Sensitivity C-reactive Protein and Cardiovascular Disease[J].Western Journal of Traditional Chinese Medicine,2018,31(10):150-152.
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同型半胱氨酸/超敏C反应蛋白与心脑血管疾病的关系()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年10期
页码:
150-152
栏目:
出版日期:
2018-10-15

文章信息/Info

Title:
Study on the Correlation between Homocysteine/High Sensitivity C-reactive Protein and Cardiovascular Disease
文章编号:
1004-6852(2018)10-0150-03
作者:
魏灵祯
兰州市七里河区人民医院，甘肃 兰州 730020
Author(s):
WEI Lingzhen
Qilihe District People′s Hospital, Lanzhou 730020, China
关键词:
冠心病; 中风病; 同型半胱氨酸; 超敏C反应蛋白
Keywords:
coronary heart disease;  stroke;  Hcy;  hs-CRP
分类号:
R714.252
文献标志码:
B
摘要:
目的：探讨同型半胱氨酸（Hcy）、超敏C反应蛋白（hs-CRP）水平与心脑血管疾病的关系。方法：选择180例心脑血管病患者为观察组，180例健康体检者为对照组。测定2组空腹Hcy和hs-CRP水平。结果：Hcy和hs-CRP水平2组不同性别之间比较，差异均有统计学意义(P＜0.05)；2组相同性别之间比较，差异有统计学意义(P＜0.05)。脑梗死患者入院后不同时间Hcy和hs-CRP均高于对照组，差异具有统计学意义(P＜0.05)。Hcy和hs-CRP水平急性心肌梗死患者与心绞痛患者相比，差异有统计学意义(P＜0.05)。观察组入院后Hcy及hs-CRP水平随着时间推移而升高，到第3天达到最高水平，随后下降，到第21天时与入院第1天时持平。第1、21天分别与第3、7、15天相比，差异有统计学意义（P＜0.05）。结论：Hcy和hs-CRP在冠心病、脑梗死的发生、发展及预后中发挥着一定的作用，定期监测对于临床诊疗有重要价值。
Abstract:
Objective: To explore the connections between Homocysteine(Hcy)/high sensitivity C-reactive protein (hs-CRP) and of cardiovascular disease. Methods: All 180 patients with cardiovascular disease were chosen as the observation group, and 180 people who underwent physical examinations were selected as the control group, the levels of fasting Hcy and hs-CRP in different groups were detected. Results: The difference had statistical meaning in the comparisons of the levels of Hcy and hs-CRP between man and woman in both groups (P＜0.05); the difference showed statistical meaning in the comparisons among the same sexes between both groups (P＜0.05). The levels of Hcy and hs-CRP of the patients suffering cerebral infarction after being admitted into the hospitals were higher than these of the control group, and the difference showed statistical meaning (P＜0.05). The difference had statistical meaning when the levels of Hcy and hs-CRP of the patients with acute myocardial infarction were compared with these of the ones with angina pectoris (P＜0.05). The levels of Hcy and hs-CRP of the patients in the observation group increased as the time went by, they could reach the highest levels by the third day and decreased afterward, it maintained at the same level at the 21st day compared with the first day of hospitalization. The difference had statistical meaning when the first day and 21st day were compared with the third day, the seventh day and the 15th day (P＜0.05). Conclusion: Hcy and hs-CRP play a certain role in the incidence, development and the prognosis of coronary heart disease and cerebral infarction, regular monitoring shows the important values to clinical diagnosis and treatment.

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备注/Memo

备注/Memo:
收稿日期：2018-03-20 作者简介：魏灵祯(1973—)，女，主管检验师。研究方向：临床检验。
更新日期/Last Update: 2018-08-15