[1]洪琳,刘源香△.化痰祛瘀散改善颈动脉粥样硬化体质状况的临床观察[J].西部中医药,2019,32(04):103-105.
　HONG Lin,LIU Yuanxiang.Clinical Observation on Reducing-phlegm Eliminating-stagnation Powder Improving the Constitution of the Patients with Carotid Atherosclerosis[J].Western Journal of Traditional Chinese Medicine,2019,32(04):103-105.
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化痰祛瘀散改善颈动脉粥样硬化体质状况的临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年04期
页码:
103-105
栏目:
出版日期:
2019-04-15

文章信息/Info

Title:
Clinical Observation on Reducing-phlegm Eliminating-stagnation Powder Improving the Constitution of the Patients with Carotid Atherosclerosis
文章编号:
1004-6852(2019)04-0103-03
作者:
洪琳，刘源香△
山东中医药大学，山东 济南 250014
Author(s):
HONG Lin, LIU Yuanxiang△
Shandong University of Traditional Chinese Medicine, Jinan 250014, China
关键词:
颈动脉粥样硬化; 化痰祛瘀散; 辨体论治; 体质评分
Keywords:
carotid atherosclerosis;  reducing-phlegm eliminating-stagnation powder;  constitution differentiation and treatment;  constitutional scores
分类号:
R221
文献标志码:
B
摘要:
目的：观察化痰祛瘀散对颈动脉粥样硬化患者体质改善的干预作用。方法：将90例符合痰湿质或血瘀质的颈动脉粥样硬化患者随机分为观察组和对照组各45例，对照组给予阿托伐他汀钙片，10 mg/次，1次/d，口服治疗；观察组以化痰祛瘀散1剂/d，2次/d，口服治疗，连续治疗3个月后，评价临床疗效，比较2组患者中医体质评分及血脂水平。结果：观察组和对照组在治疗过程中因患者未坚持服药分别有2例、1例病例脱落，最终观察组和对照组纳入统计的病例数分别为43例和44例。中医体质评分治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异无统计学意义(P＞0.05)。体质疗效观察组为93.0%，对照组为81.8%，2组比较差异有统计学意义(P＜0.05)。2组未见明显不良反应。结论：化痰祛瘀散能有效改善颈动脉粥样硬化患者的体质状况，并降低血脂水平，有助于预防及降低心脑血管疾病的发生。
Abstract:
Objective：To observe the intervention effects of reducing-phlegm eliminating-stagnation powder in the improvement of the constitution of the patients suffering carotid atherosclerosis (CAS). Methods: All 90 CAS patients who met the criteria of phlegm-damp and blood stagnation constitutions were randomized into the observation group and the control group, 45 cases each group, the control group took atorvastatin calcium tablets, 10 mg each time, once each day; and the observation group reducing-phlegm eliminating-stagnation powder, one dose each day, twice each day, after treating for three months, to assess clinical effects, to compare the levels of blood lipid and TCM constitutional scores between both groups. Results: Two cases in the observation group and one case in the control group dropped because the patients didn’t take the medicine persistently, finally there were 43 cases and 44 cases included in the observation group and the control group. The difference had statistical meaning in the comparisons of TCM constitutional scores within two groups before and after treating (P＜0.05); the difference showed statistical meaning in the comparisons between both groups after treating (P＜0.05). There was a statistical difference in the comparisons of TC, TG and LDL-C within two groups before and after treating (P＜0.05); There was no difference in the comparisons between both groups after treating (P＞0.05). constitutional effective rate of the observation group was 93.0%, higher than 81.8% of the control group, and the difference showed statistical meaning (P＜0.05). No obvious adverse reaction happened in both groups. Conclusion: Reducing-phlegm eliminating-stagnation powder could improve constitutional state of CAS patients, reduce the levels of blood lipid, which is helpful to prevent and reduce the incidences of cardiovascular diseases.

相似文献/References:

[1]蒋永平.川丹消斑汤联合西药治疗代谢综合征颈动脉粥样硬化疗效观察[J].西部中医药,2013,26(05):100.
　JIANG Yongping.Clinical Observation on ChuanDan XiaoBanTang and Western Medicine in Treating Carotid Atherosclerosis Complicated with Metabolic Syndrome[J].Western Journal of Traditional Chinese Medicine,2013,26(04):100.
[2]邴雅珺.补阳还五汤治疗气虚血瘀型颈动脉粥样硬化疗效观察[J].西部中医药,2012,25(11):73.
　BING Ya-jun.Clinical Observation on BuYang HuanWuTang for Carotid Atherosclerosis of Qi Insufficiency and Blood Stasis Pattern[J].Western Journal of Traditional Chinese Medicine,2012,25(04):73.
[3]王晓萍,杜改焕,曹骅.中风膏对颈动脉粥样硬化患者血清炎性细胞因子及颈动脉内膜中层厚度的影响[J].西部中医药,2018,31(06):6.
　WANG Xiaoping,DU Gaihuan,CAO Hua.Effects of Stroke Ointment on Inflammatory Cytokines and Carotid intima-media Thickness of the Patients with Carotid Atherosclerosis[J].Western Journal of Traditional Chinese Medicine,2018,31(04):6.

备注/Memo

备注/Memo:
收稿日期：2018-02-27 *基金项目：山东省高等学校科技计划资助项目(编号J15LL03)；山东省重点研发计划资助项目(编号2015GSF119020)。 作者简介：洪琳(1992—)，女，在读硕士研究生。研究方向：中医脑病临床及文献研究。 △通讯作者：刘源香(1970—)，女，教授，博士学位，硕士研究生导师。研究方向：中医脑病临床与文献研究。
更新日期/Last Update: 2019-04-15