[1]马立华,蔡柏.柴芍六君加味方抑制慢性萎缩性胃炎患者胃黏膜腺体萎缩及机制研究[J].西部中医药,2019,32(07):80-82.
　MA Lihua,CAI Bo.Study on the Effects and Mechanism of Modified Chaishao Liujun Prescription in Inhibiting Gastric Mucosa Gland Atrophy of CAG Patients[J].Western Journal of Traditional Chinese Medicine,2019,32(07):80-82.
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柴芍六君加味方抑制慢性萎缩性胃炎患者胃黏膜腺体萎缩及机制研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年07期
页码:
80-82
栏目:
出版日期:
2019-07-15

文章信息/Info

Title:
Study on the Effects and Mechanism of Modified Chaishao Liujun Prescription in Inhibiting Gastric Mucosa Gland Atrophy of CAG Patients
文章编号:
1004-6852(2019)07-0080-03
作者:
马立华，蔡柏
深圳市宝安中医院(集团)，广东 深圳 518100
Author(s):
MA Lihua, CAI Bo
Baoan District TCM Hospital (Group), Shenzhen 518100, China
关键词:
慢性萎缩性胃炎; 腺体萎缩; 柴芍六君加味方; 胃复春片
Keywords:
chronic atrophic gastritis;  gland atrophy;  modified Chaishao Liujun prescription;  Weifuchun tablets
分类号:
R256
文献标志码:
B
摘要:
目的：探讨柴芍六君加味方对慢性萎缩性胃炎患者胃黏膜腺体萎缩的抑制效果及其机制。方法：将慢性萎缩性胃炎患者82例进行回顾性分析，根据治疗方式将其分为胃复春片治疗组(对照组，n=44)以及胃复春片联合柴芍六君加味方治疗组(观察组，n=38)。比较2组患者治疗效果。结果：治疗后观察组患者胃黏膜腺体萎缩分度及临床有效率优于对照组(P＜0.05)；幽门螺杆菌阴性率为84.2%，高于对照组的52.3%，且不良反应发生情况低于对照组(P＜0.05)。结论：胃复春片联用柴芍六君加味方可有效抑制慢性萎缩性胃炎患者胃黏膜腺体萎缩，其机制可能与杀灭幽门螺杆菌有关。
Abstract:
Objective: To discuss the inhibitory effects and its mechanism of modified Chaishao Liujun prescription on gastric mucosa gland atrophy of the patients with chronic atrophic gastritis (CAG). Methods: All 82 CAG patients were retrospectively analyzed, and separated into the treatment group of Weifuchun tablets (the control group, n=44) and the treatment group of Weifuchun tablets and modified Chaishao Liujun prescription (the observation group, n=38). To compare therapeutic effects between both groups. Results: After treating, the observation group was superior to the control group in gastric mucosa gland atrophy and clinical effective rate (P＜0.05); Helicobacter pylori negative rate of the observation group was 84.2%, higher than 52.3% of the control group, lower than the control group in the incidence of adverse reaction (P＜0.05). Conclusion: Weifuchun tablets and modified Chaishao Liujun prescription could effectively inhibit gastric mucosa gland atrophy of CAG patients, and its mechanism might be related to killing Hp.

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备注/Memo

备注/Memo:
收稿日期：2019-03-27作者简介：马立华(1986—)，女，硕士学位，住院医师。研究方向：慢性胃炎、胃食管反流的诊治。
更新日期/Last Update: 2019-07-15