[1]马东,陈祁青,黄军凯,等.黄芪桂枝五物汤与补阳还五汤治疗腰椎间盘突出症下肢麻木的疗效对比研究[J].西部中医药,2022,35(07):11-15.[doi:10.12174/j.issn.2096-9600.2022.07.03]
　MA Dong,CHEN Qiqing,HUANG Junkai,et al.Comparative Study on Huangqi Guizhi Wuwu Tang and Buyang Huanwu Tang in the Treatment of Lower Limb Numbness of Lumbar Disc Herniation[J].Western Journal of Traditional Chinese Medicine,2022,35(07):11-15.[doi:10.12174/j.issn.2096-9600.2022.07.03]
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黄芪桂枝五物汤与补阳还五汤治疗腰椎间盘突出症下肢麻木的疗效对比研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年07期
页码:
11-15
栏目:
临床论著
出版日期:
2022-07-15

文章信息/Info

Title:
Comparative Study on Huangqi Guizhi Wuwu Tang and Buyang Huanwu Tang in the Treatment of Lower Limb Numbness of Lumbar Disc Herniation
作者:
马东1, 陈祁青2, 黄军凯1, 杨云云1, 赵继荣2, 李中锋2, 陈文2, 马冰清2
1.甘肃中医药大学，甘肃 兰州 730030
2.甘肃省中医院
Author(s):
MA Dong1, CHEN Qiqing2, HUANG Junkai1, YANG Yunyun1, ZHAO Jirong2, LI Zhongfeng2, CHEN Wen2, MA Bingqing2
1.Gansu University of Chinese Medicine, Lanzhou 730030, China
2.Gansu Provincial Hospital of Traditional Chinese Medicine
关键词:
椎间盘移位; 腰椎; 下肢麻木; 黄芪桂枝五物汤; 补阳还五汤; 临床观察
Keywords:
disc displacement;  lumbar vertebra; lower limb numbness; clinical observation
分类号:
R243
DOI:
10.12174/j.issn.2096-9600.2022.07.03
文献标志码:
A
摘要:
目的观察黄芪桂枝五物汤与补阳还五汤治疗腰椎间盘突出症（lumbar disc herniation，LDH）下肢麻木的临床疗效。 方法将LDH下肢麻木患者100例随机分为黄芪组、补阳组、联合组（黄芪桂枝五物汤+补阳还五汤）、对照组（甲钴胺片）4组各25例。黄芪组予黄芪桂枝五物汤，每日1剂；补阳组予补阳还五汤，每日1剂；联合组予黄芪桂枝五物汤与补阳还五汤合方，每日1剂；对照组予甲钴胺片每次0.5 mg，每日3次。各组均治疗2周。比较各组治疗前、治疗1周、治疗2周及治疗后4周患者40 g压力针刺感觉试验评分、10 g棉签试验评分、麻木视觉模拟（visual analog scale，VAS）评分、改良Macnab疗效比较。 结果治疗2周开始，4组患者压力针刺试验评分、棉签试验评分均较治疗前及治疗1周提高（P＜0.05）；各组麻木VAS评分治疗1周时均较治疗前降低（P＜0.05），且各时间点评分均较前一时间点降低（P＜0.05）；联合组各项指标改善情况均优于黄芪组、补阳组及对照组（P＜0.05）；4组患者治疗后改良Macnab疗效显示：黄芪组、补阳组、联合组、对照组有效率分别是84.0%、84.0%、88.0%和80.0%，差异有统计学意义（P＜0.05）。 结论黄芪桂枝五物汤和补阳还五汤单独使用可有效缓解LDH患者疼痛及下肢麻木等症状，两方疗效相当，而两方合用效果优于单独使用。
Abstract:
ObjectiveTo observe clinical effects of Huangqi Guizhi Wuwu Tang (HGW) and Buyang Huanwu Tang (BH) in the treatment of lower limb numbness of lumbar disc herniation (LDH). MethodsA total of 100 patients were randomized into Huangqi group, Buyang group, the combination group (HGW and BH) and the control group (mecobalamine tablet), with 25 cases in each group. Huangqi group took HGW, one dose each day; Buyang group BH, one dose each day; and the combination group HGW and BH, one dose each day; the control group was given mecobalamine tablet, 0.5 mg each time, three times each day. All the were treated for two weeks. To compare the scores of 40 g pressure acupuncture sensation test, the scores of 10 g cotton swab test, VAS scores and clinical effects of modified Macnab between different groups before the treatment, after one week, two weeks and four weeks of treatment. ResultsAfter two weeks of treatment, the scores of pressure acupuncture sensation test and cotton swab test in four groups raised compared with these before treating and after one week of treatment (P<0.05); VAS scores of numbness in different groups lowered after one week of treatment compared with these before treatment (P<0.05), the scores lowered at different point in time than the former one (P<0.05); the improvements of different indexes in the combination group were superior to these of Huangqi group, Buyang group and the control group (P<0.05); clinical effects of modified Macnab in four groups after the treatment showed: the effective rates of Huangqi group, Buyang group, the combination group and the control group were 84.0%, 84.0%, 88.0% and 80.0% respectively, and the difference had statistical meaning (P<0.05). ConclusionSingle use of Huangqi Guizhi Wuwu Tang or Buyang Huanwu Tang could effectively relieve pain and limb numbness in LDH patients, and both show therapeutic equivalence. The combination of both prescriptions are superior to single use.

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备注/Memo

备注/Memo:
马东（1992—），男，在读硕士研究生。研究方向：骨伤科疾病的中医药防治。甘肃省中医药管理局中医临床研究课题（GZK-2018-35）。
更新日期/Last Update: 2022-07-15