[1]李玉蒙,林柳兵,李毅平.基于数据挖掘的胃痛主要中医证型用药规律分析[J].西部中医药,2022,35(09):85-90.[doi:10.12174/j.issn.2096-9600.2022.09.16]
　LI Yumeng,LIN Liubing,LI Yiping.The Medication Law of the Main TCM Patterns of Stomachache Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2022,35(09):85-90.[doi:10.12174/j.issn.2096-9600.2022.09.16]
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基于数据挖掘的胃痛主要中医证型用药规律分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年09期
页码:
85-90
栏目:
出版日期:
2022-09-15

文章信息/Info

Title:
The Medication Law of the Main TCM Patterns of Stomachache Based on Data Mining
作者:
李玉蒙, 林柳兵, 李毅平
上海中医药大学附属市中医医院，上海 200071
Author(s):
LI Yumeng, LIN Liubing, LI Yiping
Shanghai City Hospital of Traditional Chinese Medicine, Shanghai 200071, China
关键词:
胃痛; 主要中医证型; 用药规律; 数据挖掘; 关联规则
Keywords:
stomachache; main patterns; medication laws; data mining; association rules
分类号:
R256.33
DOI:
10.12174/j.issn.2096-9600.2022.09.16
摘要:
目的探讨胃痛及其主要中医证型的用药规律。 方法以中国知网、万方数据知识服务平台、维普、中国生物医学文献服务系统中公开发表的文献为依据，借助SPSS 20.0与IBM SPSS Modeler 14.1软件，对胃痛高频中药与脾胃虚寒型胃痛、胃阴亏虚型胃痛、肝气犯胃型胃痛进行关联规则分析，探索胃痛及其主要证型的用药规律。 结果共涉及方剂266首，中药134味，胃痛的中医药相关研究涉及中医证型最多的前3位是脾胃虚寒、胃阴亏虚、肝气犯胃，使用频次最多的中药分别是白芍、陈皮、香附，得到胃痛高频中药关联规则7条；脾胃虚寒型胃痛使用最多的中药是桂枝、白术、黄芪，得到关联规则13条；胃阴亏虚型胃痛使用频次居于前3位的中药是麦冬、北沙参、白芍，得到关联规则15条；肝气犯胃型胃痛使用频次最多的中药是柴胡、枳壳、香附，得到关联规则7条。 结论治疗胃痛的中药以疏肝类、健脾类为主，中药关联规则主要以四逆散类方、桂枝加黄芪汤类方、四君子汤类方为主；脾胃虚寒型胃痛的中药多具有温阳健脾益气之效，关联规则包括的类方是理中丸类方、桂枝半夏汤类方、桂枝加黄芪汤类方、逍遥散类方、厚朴温中汤类方，药对有温阳健脾药对、温中补虚药对、健脾化痰药对；胃阴亏虚型胃痛的中药多具有养阴益胃生津作用，主要类方有一贯煎类方、酸甘化阴类方，药对有滋阴药对、健胃消食药对、疏肝理气药对、疏肝泻热药对；肝气犯胃型胃痛的中药以疏肝理气止痛为主，类方是四逆散类方，药对有疏肝行气止痛药对、柔肝行气药对、活血行气止痛药对。
Abstract:
ObjectiveTo discuss the medication law of stomachache and its main TCM patterns. MethodsBy taking the published literature in CNKI, Wanfang, VIP and CBM as the reference, via SPSS 20.0 and IBM SPSS Modeler 14.1 software, the association rules of high-frequency herbs for stomachache, stomachache of spleen-stomach cold-deficiency pattern, stomachache of stomach Yin depletion and deficiency pattern, and stomachache of liver-Qi attacking stomach pattern were analyzed, to survey the medication laws of stomachache and its main patterns. ResultsAll 266 prescriptions and 134 herbs were involved, the top three patterns of stomachache in TCM study were spleen-stomach cold-deficiency pattern, stomach Yin depletion and deficiency and liver-qi attacking stomach, the most frequently used herbs were Baishao (Paeoniae Radix Alba), Chenpi(Citri Reticulatae pericarpium) and Xiangfu (Cyperi Rhizoma), seven association rules of high-frequency herbs were obtained for stomachache; the most frequently used herbs for spleen-stomach cold-deficiency pattern stomachache were Guizhi (Cinnamomi Ramulus), Baizhu (Atractylodis Macrocephalae Rhizoma) and Huangqi (Astragali Radix), and 13 association rules were obtained; the most frequently used herbs for stomach Yin depletion and deficiency pattern stomachache contained Maidong (Ophiopogonis Radix), Beishashen (Glenhniae Radix) and Baishao (Paeoniae Radix Alba), and 15 association rules were gained; the most frequently used herbs for liver-Qi attacking stomach pattern stomachache included Chaihu(Bupleuri Radix), Zhiqiao (Aurantii Fructus) and Xiangfu, and seven association rules were gained. ConclusionThe herbs for stomachache are of soothing liver and invigorating spleen mainly, and the association rules of herbs are principally the similar prescriptions of Sini powder, Guizhi Jia Huangqi decotion, Sijunzi decoction; the herbs for spleen-stomach cold-deficiency pattern stomachache mostly could warm Yang, invigorate spleen and benefit Qi, the similar prescriptions contained in association rule are Lizhong pills, Guizhi Banxia decoction, Guizhi Jia Huangqi decoction, Xiaoyao powder and Houpo Wenzhong decoction, and the drug pairs are of warming Yang and invigorating spleen, warming the middle-energizer and tonifying deficiency, invigorating spleen and resolving phlegm; the herbs for stomach Yin depletion and deficiency pattern stomachache could nourish Yin, benefit the stomach and produce body fluid mostly, and the main prescriptions contain the ones of Yiguan Jian, and sour-sweet drugs transforming into Yin, drug pairs are of nourishing Yin, improving digestion, soothing liver and regulating Qi, soothing liver and clearing heat; the herbs for liver-Qi attacking stomach pattern stomachache could soothe liver, regulate Qi and stop pain, and the prescriptions are similar to Sini powder, and the drug pairs are of soothing liver, moving Qi, and stopping pain, of nourishing liver and moving Qi, of activating blood, moving Qi and stopping pain.

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备注/Memo

备注/Memo:
李玉蒙（1994—），男，在读硕士研究生，医师。研究方向：消化系统疾病的临床与基础研究。上海市“中医经典病房建设试点”项目［ZY（2018—2020）-FWTX-6007］；上海市中医优势病种培育项目（ZYBZ-201711）；上海市进一步加快中医药事业发展三年行动计划。
更新日期/Last Update: 2022-10-08