[1]薛羽白,朱垚,陆明.基于K-均值聚类老年病中药干预的群集功效与组方特点[J].西部中医药,2023,36(10):81-88.[doi:10.12174/j.issn.2096-9600.2023.10.18]
　XUE Yubai,ZHU Yao,LU Ming.Cluster Efficacy and the Characteristics of Formulations of Herbal Interventions for Senile Diseases Based on K-means Clustering[J].Western Journal of Traditional Chinese Medicine,2023,36(10):81-88.[doi:10.12174/j.issn.2096-9600.2023.10.18]
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基于K-均值聚类老年病中药干预的群集功效与组方特点
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年10期
页码:
81-88
栏目:
出版日期:
2023-10-15

文章信息/Info

Title:
Cluster Efficacy and the Characteristics of Formulations of Herbal Interventions for Senile Diseases Based on K-means Clustering
作者:
薛羽白, 朱垚, 陆明
南京中医药大学，江苏 南京 210023
Author(s):
XUE Yubai, ZHU Yao, LU Ming
Nanjing University of Chinese Medicine, Nanjing 210023, China
关键词:
数据挖掘; K-means; 聚类分析; 老年病; 临床经验
Keywords:
data mining; K-means; cluster analysis; senile disease; clinical experience
分类号:
R592
DOI:
10.12174/j.issn.2096-9600.2023.10.18
文献标志码:
A
摘要:
目的采用数据挖掘技术对中医辨治老年病的临床医案数据进行解构，从中研究中药运用与组方规律。 方法基于K-均值（K-means）聚类的挖掘方法，对目标医案数据库进行药物、方剂两个维度的挖掘分析与临床解构。 结果本次研究涉及医案166人次，383诊次，临床症状292种，药物358种。K-means聚类运算挖掘后，药物K-means聚类39类，方剂K-means聚类20类。 结论名老中医辨治老年病用药主要脏腑为肝、肾，配伍注重多脏合治，对气滞、血虚、阴虚复合辨证，兼顾补肾、平肝、健脾的扶正药物与清热、利湿、散结祛邪之品组合运用，方剂结构多为复法小方，以四君子汤、天麻钩藤饮为核心基础加减化裁，常复合偏于补肾的六味地黄丸、知柏地黄丸，偏于补肝的独活寄生汤，偏于安神的酸枣仁汤。
Abstract:
ObjectiveTo analyze the data of clinical medical cases of differentiating and treating senile disease by TCM using data mining, thereby studying the laws of herbal application and formulation. MethodsClinical deconstruction and excavation analysis of the targeted clinical medical databases were carried out from medicine and prescriptions based on the digging methods of K-means clustering. ResultsThe study involves 166 persons in medical cases, and 383 times of consultations, 292 clinical symptoms and 358 medicines. 39 sorts of drug K-means clustering and 20 kinds of prescription K-means clustering were found after mining with K-means clustering algorithm. ConclusionThe main viscera are liver and kidney when famous veteran TCM doctors differentiate senile diseases, the compatibility of medicines focuses on the combined treatment of the viscera. They differentiate Qi stagnation, blood deficiency and Yin deficiency together, considering the combined application of the medicines of enhancing healthy Qi such as tonifying kidney, soothing liver and invigorating spleen, with the ones of clearing heat, resolving dampness, removing nodules and eliminating the evil factors, the prescriptions frequently refer to modified Sijunzi decoction and Tianma Gouteng drink as the core, combined with Liuwei Dihuang pills and Zhibo Dihuang pills which could tonify the kidney, Duhuo Jisheng Tang which could tonify the liver and Suanzaoren Tang which could calm the spirit, and these are small compounds.

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备注/Memo

备注/Memo:
薛羽白（2000—），女，学生。研究方向：肾病的中医诊治。△；朱垚（1979—），男，博士学位，副教授。研究方向：国医大师周仲英学术思想研究、中医内科急症研究及中医大数据信息处理。江苏省六大人才高峰项目（RJFW-40）；江苏省“333高层次人才培养工程”〔（2018）Ⅲ-0121〕；江苏省科技型企业技术创新资金（BC2015022）；南京中医药大学横向课题（2019035）。
更新日期/Last Update: 1900-01-01