[1]王玥,栗枭杰,吴朝旭,等.贫血对晚期胃癌患者预后及生活质量的影响[J].西部中医药,2023,36(11):101-105.[doi:10.12174/j.issn.2096-9600.2023.11.22]
　WANG Yue,LI Xiaojie,WU Chaoxu,et al.Influence of Anemia on the Prognosis and Quality of Life of Patients with Advanced Gastric Cancer[J].Western Journal of Traditional Chinese Medicine,2023,36(11):101-105.[doi:10.12174/j.issn.2096-9600.2023.11.22]
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贫血对晚期胃癌患者预后及生活质量的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年11期
页码:
101-105
栏目:
出版日期:
2023-11-15

文章信息/Info

Title:
Influence of Anemia on the Prognosis and Quality of Life of Patients with Advanced Gastric Cancer
作者:
王玥, 栗枭杰, 吴朝旭, 侯丽
北京中医药大学东直门医院血液肿瘤科，北京 100700
Author(s):
WANG Yue, LI Xiaojie, WU Chaoxu, HOU Li
Department of Hematology and Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
关键词:
晚期胃癌; 贫血; 生存期; 生活质量
Keywords:
advanced gastric cancer; anemia; survival period; quality of life
分类号:
R573
DOI:
10.12174/j.issn.2096-9600.2023.11.22
文献标志码:
A
摘要:
目的探讨贫血对晚期胃癌患者预后及生活质量的影响。 方法依据晚期胃癌患者入组时基线血红蛋白值将其分为轻度贫血组、中重度贫血组与非贫血组，通过晚期胃癌患者中位生存时间观察贫血对患者预后的影响；将晚期胃癌患者根据中药干预时间，以3个月为界，分为足量暴露组（3个月以上）和非足量暴露组（不足3个月），分析中药暴露对晚期胃癌贫血患者预后的影响；采用《肿瘤常见症状及中医症状调查表》评估晚期胃癌患者症状及其生活质量。 结果贫血与晚期胃癌患者生活质量和生存预后呈负相关；相较于非贫血患者，肿瘤合并贫血患者具有预后不良、临床症状严重、生活质量差等特点。 结论中医药可能通过提高患者血红蛋白水平来改善患者预后。
Abstract:
ObjectiveTo discuss the influence of anemia on the prognosis and quality of life of patients with advanced gastric cancer. MethodsThe patients with advanced gastric cancer were divided into mild anaemia group, moderate to severe anaemia group and non-anaemia group according to the baseline hemoglobin values at enrolment, to observe the effects of anemia on the prognosis of the patients by their median survival time; according to the intervention time of TCM, the patients, based on a three-month period, were separated into full exposure group (longer than three months) and non-fully exposed group (less than three months), to analyze the impacts of TCM exposure on the prognosis of the patients; questionnaire on common symptoms of tumor and TCM symptoms was adopted to assess the influence of symptoms on the patients’ quality of life. ResultsAnemia was negatively associated with quality of life and survival prognosis in gastric cancer patients; compared with non-anemia patients, the patients with tumor and anemia showed the characteristics of poor prognosis, severe clinical symptoms and poor quality of life. ConclusionTCM could improve the prognosis possibly through raising the levels of hemoglobin.

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备注/Memo

备注/Memo:
王玥（1995—），女，硕士学位。研究方向：恶性肿瘤的中西医结合防治。国家自然科学基金面上项目（81573959）；2019年北京市落实中央引导地方科技发展专项（Z191100008319006）。
更新日期/Last Update: 2023-11-15