[1]张新荣,徐国梅,袁姣姣,等.中药及其提取物治疗痤疮的作用靶点探析[J].西部中医药,2023,36(11):157-161.[doi:10.12174/j.issn.2096-9600.2023.11.36]
　ZHANG Xinrong,XU Guomei,YUAN Jiaojiao,et al.Exploration into the Targets of Action of Traditional Chinese Medicine and Its Extract in the Treatment of Acne[J].Western Journal of Traditional Chinese Medicine,2023,36(11):157-161.[doi:10.12174/j.issn.2096-9600.2023.11.36]
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中药及其提取物治疗痤疮的作用靶点探析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年11期
页码:
157-161
栏目:
出版日期:
2023-11-15

文章信息/Info

Title:
Exploration into the Targets of Action of Traditional Chinese Medicine and Its Extract in the Treatment of Acne
作者:
张新荣1, 徐国梅2, 袁姣姣1, 梁娜1, 陆东亚1
1.北京中医药大学，北京 100029
2.北京中医药大学第三附属医院，北京 100029
Author(s):
ZHANG Xinrong1, XU Guomei2, YUAN Jiaojiao1, LIANG Na1, LU Dongya1
1.Beijing University of Chinese Medicine, Beijing 100029, China
2.The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100029, China
关键词:
痤疮; 中药提取物; 靶点; 综述
Keywords:
acne; TCM extract; targets; review
分类号:
R751.05
DOI:
10.12174/j.issn.2096-9600.2023.11.36
文献标志码:
A
摘要:
综述中药及其提取物治疗痤疮的动物实验及临床研究，从信号通路及炎症因子角度总结中药及其提取物治疗痤疮的作用靶点，提出MAPK/NF-κB、PI3K/Akt、TGF-β/Smad信号通路及炎症因子为其共性作用靶点，可为今后中药及提取物治疗痤疮的实验设计和新药研制提供依据。
Abstract:
By reviewing animal experiments and clinical study on TCM and its extracts, the paper summarized the targets of action of TCM and its extracts in the treatment of acne from the perspectives of signaling pathway and inflammatory factors, proposing that MAPK/NF-κB, PI3K/AKT, TGF-β/Smad signaling pathways and inflammatory factors were their common targets of action, and it could provide the reference for experimental design and the development of new drugs of TCM and its extracts in the treatment of acne in the future.

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备注/Memo

备注/Memo:
张新荣（1995—），女，硕士学位。研究方向：皮肤病的中西医结合诊治。“首都临床特色应用研究”专项（Z131107002213141）；北京中医药大学民族医药研究专项（2011MZYY-13）。
更新日期/Last Update: 2023-11-15