[1]张琨,吴升伟,周玉芳,等.探讨南方地区单相抑郁与双相抑郁患者的五运六气禀赋特点[J].西部中医药,2025,38(09):41-45.[doi:10.12174/j.issn.2096-9600.2025.09.09]
　ZHANG Kun,WU Shengwei,ZHOU Yufang,et al.The Characteristics of the Endowment of Unipolar and Bipolar Depression Based on Five Phases and Six Climatic Factors in Southern China[J].Western Journal of Traditional Chinese Medicine,2025,38(09):41-45.[doi:10.12174/j.issn.2096-9600.2025.09.09]
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探讨南方地区单相抑郁与双相抑郁患者的五运六气禀赋特点()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年09期
页码:
41-45
栏目:
调查分析
出版日期:
2025-09-15

文章信息/Info

Title:
The Characteristics of the Endowment of Unipolar and Bipolar Depression Based on Five Phases and Six Climatic Factors in Southern China
作者:
张琨1,2, 吴升伟2, 周玉芳2, 叶君荣2, 徐琰2
1.祁东县中医医院，湖南 衡阳 421600
2.广州医科大学附属脑科医院，广东 广州 510370
Author(s):
ZHANG Kun1,2, WU Shengwei2, ZHOU Yufang2, YE Junrong2, XU Yan2
1.Qidong County Hospital of TCM, Hengyang 421600, China
2.The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou 510370, China
关键词:
单相抑郁; 双相抑郁; 五运六气; 禀赋
Keywords:
unipolar depression; bipolar depression; five phases and six climatic factors; endowment
分类号:
R226
DOI:
10.12174/j.issn.2096-9600.2025.09.09
文献标志码:
A
摘要:
目的研究南方地区单、双相抑郁患者五运六气禀赋分布特点，为揭示疾病发生规律及临床研究提供新思路。 方法纳入广州医科大学附属脑科医院住院部收治的单相抑郁患者537例，双相抑郁患者179例及湖南省某镇体检健康人群即健康对照者529例，根据出生日期推算每个研究对象的五运六气禀赋，包括岁运、主运、客运、主气、客气、司天、在泉，以健康对照组为因变量的参照水平，得出单相抑郁、双相抑郁患者出生禀赋的五运六气规律。 结果1）单相抑郁：禀赋岁运水罹患单相抑郁的风险高于岁运火、土、金（P＜0.01）；禀赋司天太阳寒水罹患单相抑郁的风险高于司天少阴君火、太阴湿土、阳明燥金（P＜0.05）；禀赋在泉厥阴风木、太阴湿土罹患单相抑郁的风险高于在泉太阳寒水（P＜0.05）。2）双相抑郁：禀赋司天太阳寒水罹患双相抑郁的风险高于司天少阴君火，禀赋在泉太阳寒水罹患双相抑郁的风险高于在泉阳明燥金（P＜0.05）。 结论单、双相抑郁的罹患与五运六气禀赋存在一定关联；单相抑郁罹患风险与出生时全年气候变化密切相关；治疗抑郁症可以考虑从肺脾论治。
Abstract:
ObjectiveTo provide new thinking for clinical study and the discovery of the laws of disease occurrence by studying the characteristics of the endowment of unipolar and bipolar depression in Southern China based on five phases and six climatic factors. MethodsA total of 537 patients suffering unipolar depression and 179 ones with bipolar depression admitted into the inpatient department of the Affiliated Brain Hospital of Guangzhou Medical University, and 529 healthy people undergoing physical examination as healthy controls in a town of Hunan province were included in the study. Each patient’s endowment based on five phases and six climatic factors was calculated according to the date of birth, including annual movement, principal movement, and guest movement, principal Qi, guest Qi, heavenly master and current spring, to obtain the law of five phases and six climatic factors in the endowment of the patients suffering unipolar and bipolar depression by taking the dependent variable of the healthy control group as the reference level. Results1)unipolar depression: the risk of developing unipolar depression when the patients were born in the year of water as the annual movement was higher than the ones in the year of fire, earth and gold (P<0.01); the persons under Taiyang cold water governing the heaven exhibit a higher risk of developing unipolar depression compared to these under Shaoyin monarch fire, Taiyin damp earth and Yangming dry gold (P<0.05); the risk of developing unipolar depression is higher in people born in Jueyin wind wood/Taiyin damp earth as the current spring compared to the one in Taiyang cold water (P<0.05). 2) bipolar depression: the persons under Taiyang cold water governing the heaven present a higher risk of developing bipolar depression compared to these under Shaoyin monarch fire, and higher compared to these under Yangming dry gold (P<0.05). ConclusionThere is some correlation between the risk of unipolar and bipolar depression, and the endowment based on five phases and six climatic factors; the risk of developing unipolar depression is closely related to climate change for the year of birth; and the treatment of depression could be considered from the perspective of lung and spleen.

备注/Memo

备注/Memo:
张琨（1982—），女，硕士学位，主治医师。研究方向：神志病的中医药防治。Email：1878124678@qq.com。国家自然科学基金（81503475，82004226）；广东省自然科学基金（2016A030313491）。
更新日期/Last Update: 2025-09-15