[1]姜华,詹文强,张丽.藏药镰形棘豆4种提取物的分离以及止咳祛痰作用的研究*[J].西部中医药,2014,27(03):16-18.
 JIANG Hua,ZHAN Wenqiang,ZHANG Li.Research on the Separation of Four Kinds of Extracts in Tibetan Medicine LianXing JiDou and its Functions[J].Western Journal of Traditional Chinese Medicine,2014,27(03):16-18.
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藏药镰形棘豆4种提取物的分离以及止咳祛痰作用的研究*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年03期
页码:
16-18
栏目:
方药·药理研究
出版日期:
2014-03-15

文章信息/Info

Title:
Research on the Separation of Four Kinds of Extracts in Tibetan Medicine LianXing JiDou and its Functions
文章编号:
1004-6852(2014)03-0016-03
作者:
姜华1詹文强1张丽2
1 甘肃省中医药研究院,甘肃 兰州 730050; 2 甘肃中医学院
Author(s):
JIANG Hua1 ZHAN Wenqiang1 ZHANG Li2
1 Gansu Provincial Academy of Chinese Medicine, Lanzhou 730050, China; 2 Gansu University of Traditional Chinese Medicine
关键词:
镰形棘豆提取物止咳祛痰
Keywords:
LianXing JiDou extracts stop the cough dispel the phlegm
分类号:
R284.1
文献标志码:
A
摘要:
目的:对镰形棘豆氯仿、乙酸乙酯、正丁醇以及挥发油4个部位进行提取并对各提取物进行止咳、祛痰的药效比较研究。方法:通过小鼠氨水引咳实验观察各提取物的止咳作用;通过小鼠气管酚红排泌实验观察各提取物的祛痰作用。结果:与正常对照组比较,镰形棘豆各提取物组均能显著延长小鼠咳嗽潜伏期和减少咳嗽次数(P<0.01或P<0.05),并增加小鼠气道酚红排泌量(P<0.01)。结论:镰形棘豆氯仿、乙酸乙酯、正丁醇以及挥发油4个部位提取物均具有止咳、祛痰的作用,尤以氯仿提取物作用效果最好。
Abstract:
Objective: To extract chloroform, ethyl acetate, n-butyl alcohol and volatile oil from Tibetan medicine LianXing JiDou(Oxytropis falcata Bunge.) and compare the effects of different extracts. Methods: Mice models were induced by ammonia and administered with the extracts to observe the functions of stopping the cough; its function of dispelling the phlegm was observed by phenol sulfonphthalein excretion method in trachea of mice. Results: Compared with normal control group, different extracts from LianXing JiDou could obviously prolong the incubation period of cough and reduce the times of cough (P<0.01 or P<0.05), and increase phenol sulfonphthalein excretion quantity of trachea in mice(P<0.01). Conclusion: Chloroform, ethyl acetate, n-butyl alcohol and volatile oil from Tibetan medicine LianXing JiDou could stop the cough and dispel the phlegm, especially the extracts of chloroform showing the best effects.

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备注/Memo

备注/Memo:
收稿日期:2013-09-11*基金项目:国家自然科学基金项目(编号 81260633)作者简介:姜华(1959—),女,硕士研究生导师,博士学位,研究员,主任药师。研究方向:中(藏)药有效成分筛选及质量分析。
更新日期/Last Update: 2014-03-15