[1]付伟光,齐振勇,李爱军,等.HCY、HS-CRP、LP(a)及 D- 二聚体联合检测在冠心病病程中动态检测意义的研究*[J].西部中医药,2014,27(08):148-151.
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HCY、HS-CRP、LP(a)及 D- 二聚体联合检测在冠心病病程中动态检测意义的研究*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年08期
页码:
148-151
栏目:
报道·诊断剖析
出版日期:
2014-08-15

文章信息/Info

文章编号:
1004-6852(2014)08-0028-03
作者:
付伟光齐振勇李爱军付静怡葛俊丽
寿光市人民医院,山东 寿光 262700
关键词:
同型半胱氨酸、血清超敏C-反应蛋白、脂蛋白a和D-二聚体冠心病
分类号:
R541.4
摘要:
目的:探讨同型半胱氨酸(HCY)、血清超敏C-反应蛋白(HS-CRP)、脂蛋白a[LP(a)]和D-二聚体(DD)联合检测在冠心病病程中应用的意义。方法:将不同类型的冠心病患者198例:急性心肌梗死(AMI)组46例、稳定型心绞痛(SAP)组54例、不稳定型心绞痛(UAP)组56例、隐匿性冠心病(无症状性心肌缺血)42例设为冠心病组,将同期体检合格的健康人216例设为对照组,分别检测血清HCY、HS-CRP、LP(a)和DD的水平。结果:冠心病组HCY、HS-CRP、LP(a)和DD含量均明显高于对照组(P<0.05),对照组上述各项指标均在正常范围内。AMI组、UAP组Hcy、HS-CRP、LP(a)和DD含量明显高于SAP组和无症状性心肌缺血组(P<0.05);Hcy、HS-CRP、LP(a)和DD含量随冠心病进展呈逐渐增高趋势;无症状性心肌缺血组,UAP组,SAP组,AMI组四项联合检测的阳性率均高于HCY,Hs-CRP,LP(a),DD单独检测的阳性率(P<0.05);无症状性心肌缺血组,UAP组,SAP组,AMI组四项联合检测的阳性率和单独检测的阳性率随病程延长均逐渐提高。结论:HCY、HS-CRP、LP(a)和DD联合检测能更好地反映冠心病患者的病情程度,可以作为评估冠心病患者病情严重程度的敏感指标,对冠心病的预防和早期诊断及动态监测病情有十分重要的临床价值。

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备注/Memo

备注/Memo:
作者简介:付伟光(1962—),男,副主任技师。研究方向:免疫学。
更新日期/Last Update: 2014-08-15