[1]易天江.中西结合治疗对不同年龄段手足口病患儿心肌酶的影响[J].西部中医药,2016,29(01):113-115.
　YI Tianjiang.Influence of Integrative Medicine on Myocardial Enzymes of the Children with Hand-foot-and-mouth Disease at Different Ages[J].Western Journal of Traditional Chinese Medicine,2016,29(01):113-115.
点击复制

中西结合治疗对不同年龄段手足口病患儿心肌酶的影响()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年01期
页码:
113-115
栏目:
出版日期:
2016-01-15

文章信息/Info

Title:
Influence of Integrative Medicine on Myocardial Enzymes of the Children with Hand-foot-and-mouth Disease at Different Ages
文章编号:
1004-6852(2016)01-0113-03
作者:
易天江
贺州市人民医院，广西 贺州 542899
Author(s):
YI Tianjiang
Hezhou Municipality People’s Hospital, Hezhou 542899, China
关键词:
手足口病; 心肌酶; 肌酸激酶同工酶(CK-MB); 中西结合
Keywords:
hand-foot-and-mouth disease;  myocardial enzymes;  CKMB;  integrative medicine
分类号:
R725.1
文献标志码:
B
摘要:
目的：对2组不同年龄段手足口病患儿进行中西医结合治疗，分析治疗前后心肌酶恢复情况。方法：对住院治疗的手足口病患儿随机抽样92例，按年龄分为A组(年龄小于3岁)和B组(年龄3岁及以上)，2组患儿均予利巴韦林，喜炎平或炎琥宁、痰热清等及水溶性维生素辅助治疗；检测治疗前后心肌酶：肌酸激酶(CK)、肌酸激酶同工酶(CKMB)、乳酸脱氢酶(LDH)、a-羟丁酸脱氢酶(HBDH)恢复情况。结果：2组患儿治疗后CK、LDH、HBDH 3项心肌酶均明显降低，与治疗前比较差异有统计学意义(P＜0.05)，而CK-MB治疗前后无明显降低(P＞0.05)；A组平均治愈出院时间和平均退热时间与B组对比，差异无统计学意义(P＞0.05)，2组临床疗效相当。结论：该治疗方案治疗不同年龄患儿手足口病疗效相近，心肌酶恢复情况近似；CK-MB对心肌病变有一定的特异性和时限性，早期检测CK-MB对判断手足口病的心肌损害意义较大。
Abstract:
Objective: To analyze myocardial enzymes recovery conditions before and after treating by treating the children with hand-foot-and-mouth disease at different ages by integrative medicine in both groups. Methods: All 92 children were randomly chosen, divided into A group (younger than three years) and B group (older than three years), both groups were treated by Chinese patent drugs including ribavirin, XiYanPing or potassium sodium dehydroandroan drographolide succinate for injection, TanReQing and hydrosoluble vitamin as adjunctive therapy; myocardial enzymes including creatine kinase (CK), CKMB, lactic dehydrogenase(LDH) and α- hydroxybutyric dehydrogenase(HBDH) were detected before and after treating, to explore the rules of myocardial enzymes in different ages. Results: CK, LDH and HBDH decreased obviously in both groups after treating, the difference showed statistical meaning when they were compared with before treating, while CK-MB presented no remarkable decrease between before and after treating (P＞0.05); the difference had no statistical meaning when A was compared with B in average healing and discharging time, average antipyretic time (P＞0.05), both groups were equivalent to clinical effects. Conclusion: Curative effects of therapeutic regimens in treating the children with hand-foot-and-mouth disease at different ages are close, the conditions of myocardial enzymes recovery are similar to each other; CKMB demonstrates certain specificity and time limit to cardiomyopathy, early detection of CKMB is meaningful to judge myocardial damage of hand-foot-and-mouth disease.

相似文献/References:

[1]林海鸿.银翘散治疗手足口病的临床观察[J].西部中医药,2013,26(06):64.
　LIN Haihong.Clinical Observation on YinQiaoSan in Treating Hand-foot-and-mouth Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(01):64.
[2]薛建军,张凌云,贾国龙,等.参附注射液对心肌缺血再灌注老年大鼠NF—κB p65及COX—2表达的影响[J].西部中医药,2012,25(08):14.
　XUE Jian-jun,ZHANG Ling-yun,JIA Guo-long,et al.Influence of ShenFu Injection on Expressions of NF-κB p65 and COX-2 in Aged Myocardial Ischemia Reperfusion Rat Model[J].Western Journal of Traditional Chinese Medicine,2012,25(01):14.
[3]刘丽霞,白龙.小儿柴桂退热颗粒治疗小儿手足口病81例[J].西部中医药,2012,25(08):68.
　LIU Li-xia,BAI Long.XiaoEr ChaiGui TuiRe Granules in Treating 81 Cases of Hand-Foot-and-Mouth Disease in Children[J].Western Journal of Traditional Chinese Medicine,2012,25(01):68.
[4]陈春.柴胡口服液联合利巴韦林分散片治疗儿童手足口病 50 例[J].西部中医药,2014,27(08):111.
[5]赵成国,秦书芝,张瑶,等.鬼箭羽抗心肌缺血作用的实验研究[J].西部中医药,2015,28(03):19.
[6]蔡钢,张选明,张辰龙,等.从“燥”论治新疆地区手足口病[J].西部中医药,2011,24(11):28.
[7]陈林伟,王琴,曹春华△,等.气血双补方对大鼠急性心肌缺血的保护作用研究[J].西部中医药,2019,32(06):4.
　CHEN Linwei,WANG Qin,CAO Chunhua,et al.Study of the Protective Effects of Qixue Shuangbu Prescription on the Rats with Acute Myocardial Ischemia[J].Western Journal of Traditional Chinese Medicine,2019,32(01):4.
[8]李宏云,胡榕,汪明辉,等.抗感颗粒（儿童装）对普通型手足口病患儿免疫功能及炎性因子的影响[J].西部中医药,2021,34(04):1.[doi:10.12174/j.issn.2096-9600.2021.04.01]
　LI Hongyun,HU Rong,WANG Minghui,et al.The Influence of Kanggan Granules (for children) on Immunologic Function and Inflammatory Factor in Children Suffering Common Hand-foot-and-mouth Disease[J].Western Journal of Traditional Chinese Medicine,2021,34(01):1.[doi:10.12174/j.issn.2096-9600.2021.04.01]

备注/Memo

备注/Memo:
作者简介：易天江(1970—)，男，副主任医师。研究方向：儿科疾病的诊治。
更新日期/Last Update: 2016-01-15