[1]邓建忠,马维维.黄龙止咳颗粒联合氨溴索口服液治疗反复呼吸道感染78例[J].西部中医药,2018,31(12):77-79.
　DENG Jianzhong,MA Weiwei.HuangLong Cough-Relieving Granules Combined with Ambroxol Oral Liquid in Treating 78 Cases of Recurrent Respiratory Tract Infection[J].Western Journal of Traditional Chinese Medicine,2018,31(12):77-79.
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黄龙止咳颗粒联合氨溴索口服液治疗反复呼吸道感染78例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年12期
页码:
77-79
栏目:
出版日期:
2018-12-15

文章信息/Info

Title:
HuangLong Cough-Relieving Granules Combined with Ambroxol Oral Liquid in Treating 78 Cases of Recurrent Respiratory Tract Infection
文章编号:
1004-6852(2018)12-0077-03
作者:
邓建忠1，马维维2
1 汉中市南郑区人民医院 陕西 汉中 723100； 2 汉中市中心医院
Author(s):
DENG Jianzhong1, MA Weiwei2
1 Nanzheng District People's Hospital, Hanzhong 723100, China; 2 Hanzhong Municipality Central Hospital
关键词:
反复呼吸道感染; 黄龙止咳颗粒; 氨溴索口服液; 免疫功能; 不良反应
Keywords:
recurrent respiratory tract infection;  HuangLong cough-relieving granules;  ambroxol oral liquid;  immune function;  adverse reaction
分类号:
R373.1
摘要:
目的：观察黄龙止咳颗粒联合氨溴索口服液治疗反复呼吸道感染的临床疗效。方法：将155例反复呼吸道感染患儿根据给药方案分为对照组77例和观察组78例，对照组给予氨溴索口服液治疗，观察组在对照组治疗的基础上口服黄龙止咳颗粒治疗，比较2组总有效率、症状及体征消失时间、治疗前后免疫功能各指标变化及不良反应发生率。结果：总有效率观察组为96.15%，对照组为83.12%，2组比较差异有统计学意义(P＜0.05)。咳嗽消失时间、咯痰消失时间、退热时间及肺部啰音消失时间2组间比较，差异有统计学意义(P＜0.05)。CD4+、CD8+及CD4+/CD8+治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后2组组间比较差异也有统计学意义(P＜0.05)。不良反应发生率观察组为3.85%，对照组为5.19%，2组比较差异无统计学意义(P＞0.05)。结论：黄龙止咳颗粒联合氨溴索口服液可有效改善患者临床症状，提高机体免疫功能，临床疗效显著，且不良反应轻微，在反复呼吸道感染患儿治疗中具有重要的临床意义。
Abstract:
Objective：To observe clinical effects of HuangLong cough-relieving granules combined with ambroxol oral liquid in treating recurrent respiratory tract infection (RRTI). Methods: All 155 children were allocated to 77 cases of the control group and 78 cases of the observation group according to medication regimen, the control group were treated by ambroxol oral liquid, the observation group took HuangLong cough-relieving granules based on the therapy of Western medicine, the incidence of adverse reaction, the alterations of the indexes of immune function before and after treating, disappearing time of symptom and body signs and total effective rate of both groups were compared. Results: Total effective rate of the observation group was 96.15%, higher than 83.12% of the control group, and the difference presented statistical meaning(P＜0.05). The difference had statistical meaning in the disappearing time of cough, expectorating, fever and pulmonary rale between both groups(P＜0.05).The difference was statistically significant in CD4+, CD8+ and CD4+/ CD8+ within two groups before and after treating (P＜0.05); the difference had statistical meaning in these indexes between both groups after treating(P＜0.05). The incidence of adverse reaction of the observation group was 3.85%, lower than 5.19% of the control group, and the difference had no statistical meaning(P＞0.05). Conclusion: HuangLong cough-relieving granules combined with ambroxol oral liquid could effectively improve clinical symptoms of the children, raise body immune function with notable effects and minor adverse reaction, and it possesses the important clinical meaning in treating RRTI children.

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备注/Memo

备注/Memo:
收稿日期：2018-08-27 作者简介：邓建忠(1970—)，男，副主任医师。研究方向：儿科疾病的治疗。
更新日期/Last Update: 2018-12-15