[1]张玉梅,杨丽霞△,孟祥云.基于CNKI数据库分析葛根素治疗糖尿病的研究现状[J].西部中医药,2019,32(06):57-59.
　ZHANG Yumei,Yang Lixia,Meng Xiangyun.Current State of Puerarin in the Treatment for Diabetes Mellitus Based on CNKI Database[J].Western Journal of Traditional Chinese Medicine,2019,32(06):57-59.
点击复制

基于CNKI数据库分析葛根素治疗糖尿病的研究现状
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年06期
页码:
57-59
栏目:
出版日期:
2019-06-15

文章信息/Info

Title:
Current State of Puerarin in the Treatment for Diabetes Mellitus Based on CNKI Database
文章编号:
1004-6852(2019)06-0057-03
作者:
张玉梅1，杨丽霞2△，孟祥云3
1 兰州市西固区人民医院，甘肃 兰州 730060； 2 甘肃省中医药研究院； 3 甘肃省中医院
Author(s):
ZHANG Yumei1, Yang Lixia2△, Meng Xiangyun3
1 Xigu District People′s Hospital, Lanzhou 730060, China; 2 Gansu Provincial Academy of Chinese Medicire;3 Gansu Provincial Hospital of Traditional Chinese Medicine
关键词:
CNKI数据库; 葛根素; 糖尿病; 文献
Keywords:
CNKI database;  puerarin;  diabetes mellitus;  literature
分类号:
R587.1
文献标志码:
A
摘要:
目的：应用数据挖掘技术，分析葛根素治疗糖尿病的研究现状。方法：从中国知网检索关键词“葛根素”“糖尿病”，纳入篇名为葛根素治疗糖尿病的全部文献，然后从文献的年度分布、发表类型、学科分布、基金类型分析葛根素治疗糖尿病的文献特征；从文献的发表单位、作者、疾病分布分析葛根素治疗糖尿病的研究现状。结果：经过文献检索，发现葛根素治疗糖尿病开始于1997年，截止2017年9月，共有487篇文献。其中432篇文献发表在学术期刊上，19篇硕士论文，5篇博士学位论文，24篇国内会议论文，7篇国际会议论文。从学科分布来看，主要集中在内分泌疾病(185篇)、中药学(137篇)、中医学(97篇)、心血管系统疾病(10篇)等学科。国家自然科学基金资助20篇，各省自然科学基金13篇，各省教委基金7篇，高等学校博士学科点专项科研基金2篇；省、直辖市其他基金资助10篇。从研究机构来看，研究最多的机构是中南大学湘雅医院21篇，其次是娄底市中心医院20篇，北京中医药大学16篇，河北医科大学14篇，苏州大学12篇，牡丹江医学院10篇。研究内容主要针对糖尿病糖脂代谢异常96篇，糖尿病肾病95篇，糖尿病周围神经病变13篇，临床研究(339篇)和动物实验(132篇)均有涉及，且以临床研究为主。结论：葛根素治疗糖尿病的研究已有20年的历史，药理作用广泛，可以治疗糖脂代谢异常、糖尿病肾病、糖尿病心肌病、糖尿病周围神经病变等，尤其对糖尿病并发症的治疗效果显著。
Abstract:
Objective: To analyze the current state of puerarin in the treatment for diabetes mellitus (DM) using the technology of data mining. Methods: "Puerarin" and "diabetes mellitus (DM) " were chosen as the keywords to search in CNKI database, all the papers about puerarin in the treatment for DM were included, the characteristics of the papers were analyzed from the types of the funds, the distribution of the subjects, the publication types and annual distribution of the papers. Results: Via literature search, it was found that there were 487 articles on puerarin in the treatment for DM, beginning in 1997, ending September, 2017. Among them, 432 papers were published on academic journals, 19 papers are master′s thesis, 5 ones were doctoral thesis, 24 ones are domestic conference articles, and seven are international conference articles. From the distribution of the subjects, the papers were mainly on endocrine disease (185 articles), Chinese materia medica (137 papers), TCM (97 articles) and the disease of cardiovascular system (10 articles). There were 20 papers assisted by the National Natural Science Fund, 13 papers by provincial natural science fund, 7 ones by provincial education commission fund, 2 by special scientific research fund for doctoral program in Colleges and Universities and 10 by provincial or municipal funds. As for research institutes, there were 21 papers from Xiangya Hospital Central South University, 20 ones from Loudi city central hospital, 16 ones from Beijing University of Chinese Medicine, 14 ones from Hebei Medical University, 12 ones from soochow University and 10 ones from Mudanjiang medical University. There were 96 articles about abnormal glucose and lipid metabolism in diabetes mellitus, 95 about diabetic nephropathy, 13 on diabetic peripheral neuropathy, involving clinical study (339 articles) and zoopery (132 ones), and mainly clinical study. Conclusion: Puerarin in the treatment for DM has been studied for more than 20 years, and its pharmacological action is wide, it could be used to treat abnormal glucose and lipid metabolism in diabetes mellitus, diabetic nephropathy and diabetic peripheral neuropathy, especially effective in treating diabetic complications.

相似文献/References:

[1]张立峰.RP-HPLC法同时测定清热止嚏颗粒中黄芩苷、芍药苷和葛根素[J].西部中医药,2015,28(04):27.
[2]陈岩岩,吴清△,张庆,等.自拟晕定方提取工艺路线筛选及初步药效学研究[J].西部中医药,2015,28(09):13.
[3]王海峰,张红.不同大孔吸附树脂对葛根总黄酮分离纯化效果的影响[J].西部中医药,2015,28(11):27.
[4]穆云霞,吴宇锋.葛根素联合耳穴贴压治疗小儿近视并发斜弱视32例[J].西部中医药,2015,28(12):106.
[5]王东红,王春爱,薛建军.葛根素的研究进展[J].西部中医药,2017,30(01):139.
　WANG Donghong,WANG Chunai,XUE Jianjun.Study Development of Puerarin[J].Western Journal of Traditional Chinese Medicine,2017,30(06):139.
[6]乔莉,郑慧,杨丽霞,等.基于CNKI数据挖掘分析黄芪多糖治疗糖尿病的文献特征和研究现状[J].西部中医药,2017,30(03):56.
　QIAO Li,ZHENG Hui,YANG Lixia,et al.Analysis of Literature Characteristics and Research Status of Astragalus Polysaccharides in Treating Diabetes Based on CNKI Data Mining[J].Western Journal of Traditional Chinese Medicine,2017,30(06):56.
[7]白婧,肖会敏△,何悦,等.沙菊茶HPLC指纹图谱及7个成分溶出度的研究[J].西部中医药,2018,31(11):26.
　BAI Jing,XIAO Huimin,HE Yue,et al.Study on HPLC Fingerprint and Dissolution Rate of Seven Kinds of Ingredients of ShaJu Tea[J].Western Journal of Traditional Chinese Medicine,2018,31(06):26.
[8]石静,范强,张玉梅△.葛根素对2型糖尿病患者脂肪因子、氧化应激及胰岛素抵抗的影响[J].西部中医药,2019,32(06):86.
　SHI Jing,FAN Qiang,ZHANG Yumei.Influence of Puerarin on Adipokine, Oxidative Stress and Insulin Resistance of the Patients with Type Two Diabetes Mellitus[J].Western Journal of Traditional Chinese Medicine,2019,32(06):86.
[9]周睿娴,王光义,陈睿,等.葛根素抑制间充质干细胞成脂肪分化的作用及机制[J].西部中医药,2020,33(03):34.[doi:10.12174/j.issn.1004-6852.2020.03.09]
　ZHOU Ruixian,WANG Guangyi,CHEN Rui,et al.Effects and Mechanism of Puerarin in Inhibiting Adipogenic Differentation of Mesenchymal Stem Cells[J].Western Journal of Traditional Chinese Medicine,2020,33(06):34.[doi:10.12174/j.issn.1004-6852.2020.03.09]
[10]于妍,王春爱,李玉兰,等.葛根素通过调节钙调素依赖性蛋白激酶Ⅱ减轻布比卡因诱发的心肌损伤研究[J].西部中医药,2022,35(01):29.[doi:10.12174/j.issn.2096-9600.2022.01.06]
　YU Yan,WANG Chun'ai,LI Yulan,et al.Study on Puerarin Alleviating Myocardial Damage Induced by Bupivacaine Intoxication via Regulating Calmodulin-dependent Protein Kinase II[J].Western Journal of Traditional Chinese Medicine,2022,35(06):29.[doi:10.12174/j.issn.2096-9600.2022.01.06]

备注/Memo

备注/Memo:
收稿日期：2018-10-26*基金项目：国家自然科学基金（编号81560764）。作者简介：张玉梅(1965—)，女，主任医师。研究方向：中西医结合防治糖尿病。△通讯作者：杨丽霞(1979—)，女，博士学位，主任医师。研究方向：中医药防治糖尿病。
更新日期/Last Update: 2019-06-15