[1]孙莺,王玉梅,尉鹏,等.甘肃两种道地药材当归及党参中药饮片中微生物污染状况研究[J].西部中医药,2022,35(04):17-20.[doi:10.12174/j.issn.2096-9600.2022.04.05]
　SUN Ying,WANG Yumei,WEI Peng,et al.Study on Microbial Contamination of Two Genuine Medicinal Materials Danggui and Dangshen in Gansu Province[J].Western Journal of Traditional Chinese Medicine,2022,35(04):17-20.[doi:10.12174/j.issn.2096-9600.2022.04.05]
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甘肃两种道地药材当归及党参中药饮片中微生物污染状况研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年04期
页码:
17-20
栏目:
道地药材
出版日期:
2022-04-15

文章信息/Info

Title:
Study on Microbial Contamination of Two Genuine Medicinal Materials Danggui and Dangshen in Gansu Province
作者:
孙莺1,2, 王玉梅1,2, 尉鹏1,2, 杨平荣1,2, 谢亲建3, 郭小雨4
1.甘肃省药品检验研究院，甘肃 兰州 730000
2.国家药监局中药材及饮片质量控制研究重点实验室
3.武警甘肃省总队医院
4.西北师范大学生命科学学院
Author(s):
SUN Ying1,2, WANG Yumei1,2, WEI Peng1,2, YANG Pingrong1,2, XIE Qinjian3, GUO Xiaoyu4
1.Gansu Institute for Drug Control, Lanzhou 730000, China
2.State Drug Administration-Key Laboratory of Quality Control of Chinese Medicinal Materials and Decoction Pieces
3.Gansu Provincial General Hospital of Armed Police Force
4.College of Life Sciences, Northwest Normal University
关键词:
中药饮片; 微生物污染; 需氧菌; 霉菌; 酵母菌; 耐胆盐革兰阴性菌
Keywords:
herbal decoction pieces; microbial contamination; aerobic bacteria; mould; saccharomycetes; bile salt tolerant gram negative bacteria
分类号:
R283
DOI:
10.12174/j.issn.2096-9600.2022.04.05
文献标志码:
A
摘要:
目的研究甘肃省市售的两种道地药材当归和党参中药饮片的微生物污染状况。 方法根据《中华人民共和国药典》（2015版）微生物相应的检查方法，对两种中药材饮片共计61批样品的需氧菌总数（total aerobic microbial count，TAMC）、酵母菌和霉菌总数（total combined yeasts and molds count，TYMC）、耐胆盐革兰阴性菌及沙门菌进行检查，初步了解市售当归、党参中药饮片的微生物负载量。 结果61批中药饮片样品的对数IgTAMC值介于2.05～6.30，IgTYMC值介于0.70～3.23，47.5%的样品检出耐胆盐革兰阴性菌，当归和党参饮片所有批次均未检出沙门菌。 结论中药饮片微生物污染状况严重，饮片的微生物限度标准亟待完善，饮片生产加工过程控制亟待加强。
Abstract:
ObjectiveTo study microbial contamination of Danggui and Dangshen commercially available in Gansu province. MethodsAccording to corresponding inspection methods for microorganisms in Chinese Pharmacopoeia (edition 2015), TAMC, TYMC, bile salt tolerant Gram-negative bacteria and Salmonella in 61 batches of Danggui and Dangshen samples were tested, to primarily survey the microbial load of Danggui and Dangshen on the market. ResultsThe logarithm lgTAMC value ranged from 2.05 to 6.30, and the lgTYMC value ranged from 0.70 to 3.23 in 61 batches of herbal decoction pieces samples, bile salt resistant gram-negative bacteria were detected in 47.5% of the samples, no salmonella was tested out in Danggui and Dangshen of all the batches. ConclusionBecause of serious microbial contamination of herbal decoction pieces, microbial limit standard of decoction piece needs to be improved, and production and processing control of decoction pieces needs to be enhanced.

相似文献/References:

[1]朱玉荣.医院中药饮片质量与储存管理探讨[J].西部中医药,2014,27(10):56.
[2]王冬梅,马侗,杜明才.中药饮片质量管理方法探悉[J].西部中医药,2014,27(06):47.
　WANG Dongmei,MA Tong,DU Mingcai.Exploration of Quality Control for Chinese Herbal Pieces[J].Western Journal of Traditional Chinese Medicine,2014,27(04):47.
[3]张喜萍,邱国玉,许淑琴,等.2014—2016年甘肃省15种中药材及中药饮片质量抽样分析[J].西部中医药,2020,33(02):73.[doi:10.12174/j.issn.1004-6852.2020.02.20]
　ZHANG Xiping,QIU Guoyu,XU Shuqin,et al.Sampling Analysis of the Quality of Herbal Decoction Pieces and 15 Kinds of Chinese Herbs in Gansu Province Between 2014 and 2016[J].Western Journal of Traditional Chinese Medicine,2020,33(04):73.[doi:10.12174/j.issn.1004-6852.2020.02.20]

备注/Memo

备注/Memo:
孙莺（1981—），女，博士学位，主任药师。研究方向：药品化妆品质量控制与标准研究。2019年陇原青年创新创业人才项目；2020年中药材及饮片质量控制重点实验室项目（2020GSMPA-KL08）。
更新日期/Last Update: 2022-06-24