[1]武俊斌,张斌,贾利春.养心活血方联合尼可地尔治疗冠状动脉慢血流临床观察[J].西部中医药,2022,35(07):83-85.[doi:10.12174/j.issn.2096-9600.2022.07.22]
 WU Junbin,ZHANG Bin,JIA Lichun.Clinical Observation on Nourishing-heart Activating-blood Prescription Combined with Nicorandil in the Treatment of Coronary Slow Flow Phenomenon[J].Western Journal of Traditional Chinese Medicine,2022,35(07):83-85.[doi:10.12174/j.issn.2096-9600.2022.07.22]
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养心活血方联合尼可地尔治疗冠状动脉慢血流临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年07期
页码:
83-85
栏目:
衷中参西
出版日期:
2022-07-15

文章信息/Info

Title:
Clinical Observation on Nourishing-heart Activating-blood Prescription Combined with Nicorandil in the Treatment of Coronary Slow Flow Phenomenon
作者:
武俊斌 张斌 贾利春
天水市中西医结合医院心内科,甘肃 天水 741020
Author(s):
WU Junbin ZHANG Bin JIA Lichun
Department of Cardiology, Tianshui Hospital of Integrative Medicine, Tianshui 741020, China
关键词:
冠状动脉慢血流中西医结合养心活血方尼可地尔临床观察
Keywords:
CSFPintegrative medicinenourishing-heart activating-blood granulesnicorandilclinical observation
分类号:
R256.22
DOI:
10.12174/j.issn.2096-9600.2022.07.22
文献标志码:
B
摘要:
目的观察养心活血方联合尼可地尔治疗冠状动脉慢血流(coronary slow flow phenomenon,CSFP)的疗效。 方法将CSFP患者83例按随机数字表法分为对照组41例与治疗组42例。两组均予常规治疗,治疗组加服养心活血颗粒。治疗6个月后观察两组患者临床症状变化情况;检测治疗前后两组患者超敏C反应蛋白(hypersensitive-C-reactive protein,hs-CRP)、低密度脂蛋白胆固醇(Low-density lipoprotein cholesterol,LDL-C);应用冠脉造影心肌梗死溶栓治疗试验(thrombolysis in myocardial infarction,TIMI)血流分级国际通用校正TIMI血流帧数法(corrected TIMI frame count,CTFC)评定治疗前后两组患者CTFC值。 结果治疗后两组患者hs-CRP、LDL-C水平及临床症状评分均低于治疗前,治疗组低于对照组(P<0.05);两组治疗后CTFC值均较治疗前降低(P<0.05),治疗组低于对照组(P<0.05);治疗期间两组均未见明显不良反应。 结论养心活血方联合尼可地尔治疗CSFP疗效优于单纯尼可地尔治疗,且无明显不良反应。
Abstract:
ObjectiveTo observe clinical effects of nourishing-heart activating-blood prescription and nicorandil in the treatment of CSFP. MethodsAll 83 patients were divided into 41 cases in the control group and 42 cases of the treatment group according to random number table method. Both groups accepted conventional therapy, and the treatment group took nourishing-heart activating-blood granules. To observe the changes of clinical symptoms between both groups after six months of treatment; to detect the levels of hs-CRP and LDL-C before and after treatment between both groups; coronary angiogram was applied to assess CTFC values. ResultsAfter the treatment, the levels of hs-CRP and LDL-C, and the scores of clinical symptoms in both groups were lower than these before treatment, the treatment group was lower than the control group (P<0.05); CTFC values of both groups after the treatment were lower than these before the treatment (P<0.05), the treatment group was lower than the control group (P<0.05). No obvious adverse reaction has been found during therapeutic period. ConclusionNourishing-heart activating-blood granules and nicorandil are superior to only nicorandil in the treatment of CSFP, without obvious adverse reaction.

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备注/Memo

备注/Memo:
武俊斌(1978—),男,硕士学位,副主任医师。研究方向:心血管疾病的中西医结合诊治。
更新日期/Last Update: 2022-07-15