[1]杨坤,甘丽华,郭超峰.吴茱萸汤治疗呕吐的方证关系研究[J].西部中医药,2024,37(05):97-100.[doi:10.12174/j.issn.2096-9600.2024.05.18]
　YANG Kun,GAN Lihua,GUO Chaofeng.Study on the Formulae-syndrome Relationship in the Treatment of Vomiting by Wuzhuyu Tang[J].Western Journal of Traditional Chinese Medicine,2024,37(05):97-100.[doi:10.12174/j.issn.2096-9600.2024.05.18]
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吴茱萸汤治疗呕吐的方证关系研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年05期
页码:
97-100
栏目:
二次研究
出版日期:
2024-05-15

文章信息/Info

Title:
Study on the Formulae-syndrome Relationship in the Treatment of Vomiting by Wuzhuyu Tang
作者:
杨坤1, 甘丽华1, 郭超峰2
1.广西中医药大学，广西 南宁 530001
2.广西中医药大学基础医学院，广西 南宁 530023
Author(s):
YANG Kun1, GAN Lihua1, GUO Chaofeng2
1.Guangxi University of Chinese Medicine, Nanning 530001, China
2.School of Basic Medicine, Guangxi University of Chinese Medicine, Nanning 530023, China
关键词:
呕吐; 关联规则; 吴茱萸汤; 方证关系
Keywords:
vomiting; association rule; formulae-syndrome relationship
分类号:
R256.31
DOI:
10.12174/j.issn.2096-9600.2024.05.18
文献标志码:
A
摘要:
目的探索吴茱萸汤治疗呕吐的方证关系。 方法从中国知网数据库检索吴茱萸汤治疗呕吐的医案100个，将医案中的相关症状（体征）、治法、药物等信息进行规范化处理，建立数据库。应用关联规则数据挖掘方法分析医案中症状（体征）、药物、治法的频数、支持度、置信度、提升度及其关联关系。 结果收集到的100个医案共涉及166个症状（体征），1432频次，其中以呕吐为首出现频次较高的症状（体征）19个；共涉及75味中药，671频次，其中以吴茱萸为首出现频次较高的中药13味；共涉及治法37种，385频次，其中以“降逆”为首出现频次较高的治法7种。共涉及提升度≥1.3的症状（体征）关联规则16个，提升度≥1.2的中药关联规则6个，均具有明显的核心化倾向。 结论运用关联规则的数据挖掘方法可以较好发现吴茱萸汤及其加减方治疗呕吐的症状（体征）、药物组方及治法的关联规律，可为临床遣方用药提供依据。
Abstract:
ObjectiveTo explore the formula-syndrome relationship in the treatment of vomiting by Wuzhuyu Tang. MethodsAll 100 cases of clinical application of the formula in the treatment of vomiting were retrieved from China National Knowledge Infrastructure (CNKI), and the information of symptoms (body signs), therapeutic methods and drugs in the cases were standardized to establish the database. The data mining method was applied to analyze the frequency, support, confidence, and enhancement of symptoms (body signs), drugs, and remedies in the medical cases, and to analyze the association relationship. ResultsThe collected 100 medical cases involved 166 symptoms (signs) with the frequencies of 1432 times, among which 19 symptoms (signs) with high frequency appeared with vomiting as the first one; 75 medicines with the frequencies of 671 times, among which 13 medicines with high frequency appeared with Wuzhuyu (Euodiae fructus) as the first one; a total of 37 therapeutic methods were involved with a frequency of 385, among which seven therapeutic methods appeared more frequently with "lowering the adverse flow of Qi" as the first one. A total of 16 symptom (sign) association rules with elevation ≥1.3 and six drug association rules with elevation ≥1.2 were involved, all of which had an obvious tendency to be coregulated. ConclusionThe data mining method of association rules can be used to better discover the association rules between symptoms, drug formulae and therapeutic methods of vomiting, and Wuzhuyu Tang and its modified formulas, which can provide a basis for clinical application of the prescription and the drugs.

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备注/Memo

备注/Memo:
杨坤（1995—），男，硕士学位。研究方向：中医脾胃病及中医经方临床应用的研究。国家自然科学基金（82060915、81560820）；广西一流学科建设开放课题（2019XK004）；广西中医药大学研究生创新计划项目（YCXJ2021043）。
更新日期/Last Update: 2024-05-15