兰州地区健康人群甲胎蛋白、癌胚抗原参考值调查-《西部中医药》

文章信息/Info

Title:: Establishment of AFP and CEA Reference Ranges for Healthy People in Lanzhou

Author(s):: XING Fujun1, WANG Xiaoping2, LIU Yuanjie2, TIAN Weihua1, YAO Shaohua2, ZHA Chengxi2; 1 Gansu Provincial Academy of Chinese Medicine, Lanzhou 730050, China; 2 Gansu Provincial Hospital of Traditional Chinese Medicine

Keywords:: Lanzhou; AFP; CEA; electrochemiluminescence immunoassay (ECLI); reference ranges

摘要:: 目的：建立电化学发光法测定血清甲胎蛋白（AFP）和癌胚抗原（CEA）在兰州地区健康人群的参考值。方法：通过Roche E411电化学发光分析仪进行血清AFP和CEA检测，采用SPSS16.0建立本实验室95%可信区间。结果：兰州地区健康人群血清中AFP、CEA结果呈正态分布，男性与女性之间差异无统计学意义（P＞0.05）。正常人群AFP参考范围为0～4.33 IU/mL；CEA＞61岁为0～4.33 ng/mL，＜61岁为0～3.07 ng/mL。结论：兰州地区健康人群AFP参考范围为＜4.33 IU/mL；CEA＞61岁为＜4.33 ng/ml，＜61岁为＜3.07 ng/mL。

Abstract:: Objective: To establish normal reference ranges of AFP and CEA for healthy people in Lanzhou by electrochemiluminescence immunoassay(ECLI). Method: AFP and CEA in the serum were detected with Roche E411 electrochemiluminescence analyzer, 95% confidence intervals were found by SPSS16.0. Result: the results of AFP and CEA in the serum of healthy people showed normal distribution in Lanzhou, there was no statistical meaning between male and female(P＞0.05). AFP reference range of normal people was from 0 to 4.33 IU/mL; CEA of the people above 61 years was between 0 and 4.33 ng/mL, the range of the people under 61 years was between 0 and 3.07 ng/mL. Conclusion: AFP normal reference range of healthy people in Lanzhou is less than 4.33 IU/mL; CEA normal reference range in the people above 61 years is 4.33 ng/mL, and less than 3.07 ng/mL for the people under 61 years.