[1]卢成文,李丽,邓衍威,等.雪山胃宝丸对小鼠胃溃疡的保护作用[J].西部中医药,2016,29(01):21-25.
　LU Chengwen,LI Li,DENG Yanwei,et al.Protective Effects of XueShan WeiBao Pills on Gastric Ulcer of the Mice[J].Western Journal of Traditional Chinese Medicine,2016,29(01):21-25.
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雪山胃宝丸对小鼠胃溃疡的保护作用()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年01期
页码:
21-25
栏目:
出版日期:
2016-01-15

文章信息/Info

Title:
Protective Effects of XueShan WeiBao Pills on Gastric Ulcer of the Mice
文章编号:
1004-6852(2016)01-0021-05
作者:
卢成文1，李丽2，邓衍威1，张剑桥1，袁佳妮1，张雷明1
1 烟台大学药学院，山东 烟台 264005； 2 山东阿如拉药物研究开发有限公司
Author(s):
LU Chengwen1, LI Li2, DENG Yanwei1, ZHANG Jianqiao1, YUAN Jia′ni1, ZHANG Leiming1
1 Pharmacy College of Yantai University, Yantai 264005, China;2 Shandong Arura Drug Research and Development Co., LTD
关键词:
胃溃疡; 溃疡指数; 雪山胃宝丸
Keywords:
gastric ulcer;  ulcer index;  XueShan WeiBao pills
分类号:
R285.5
文献标志码:
A
摘要:
目的：探讨雪山胃宝丸对小鼠胃溃疡的保护作用。方法：应用无水乙醇致小鼠胃溃疡模型、吲哚美辛致小鼠胃溃疡模型及应激性胃溃疡模型，观察雪山胃宝丸对胃黏膜损伤的保护作用，计算溃疡指数和溃疡抑制率。结果：与模型组相比，雪山胃宝丸对无水乙醇致小鼠胃溃疡、吲哚美辛致小鼠胃溃疡及应激性胃溃疡具有明显保护作用(P＜0.05)。结论：雪山胃宝丸对小鼠胃溃疡有保护作用。
Abstract:
Objective: To investigate the protective effects of XueShan WeiBao pills on gastric ulcer(GU) of the mice. Methods: Mice model with GU or stress GU was established by using absolute ethyl alcohol and indometacin, to observe protective effects of XueShan WeiBao pills on gastric mucosal injury, ulcer index and index inhibition rate were calculated. Results: Compared with the model group, XueShan WeiBao pills could protect absolute ethyl alcohol-induced GU and indometacin-induced GU and stress GC obviously (P＜0.05). Conclusion: XueShan WeiBao pills present protective effects on GU of the mice.

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[1]周子权.川芎嗪联合奥美拉唑治疗老年胃溃疡60例[J].西部中医药,2013,26(09):86.
　ZHOU Ziquan.Treatment for 60 Senile Patients Suffering from Gastric Ulcer with Ligustrazine Injection and Omeprazole[J].Western Journal of Traditional Chinese Medicine,2013,26(01):86.
[2]张春燕.针对性护理提升慢性胃溃疡患者临床有效率及生活质量效果评价[J].西部中医药,2015,28(03):130.
[3]陈俊其,秦华珍,尹优,等.3味山姜属中药黄酮类成分对胃溃疡寒证大鼠胃消化液分泌的影响及作用机制研究[J].西部中医药,2023,36(02):7.[doi:10.12174/j.issn.2096-9600.2023.02.02]
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备注/Memo

备注/Memo:
作者简介：卢成文(1988—)，女，在读硕士研究生。研究方向：中药药理学。
更新日期/Last Update: 2016-01-15