[1]邓歌.放射疗法配合黄药子汤保留灌肠治疗晚期宫颈癌临床观察[J].西部中医药,2021,34(06):103-106.[doi:10.12174/j.issn.2096-9600.2021.06.25]
　DENG Ge.Clinical Observation of Radiotherapy Combined with Retention Enema with Huangyaozi Decoction in the Treatment of Advanced Cervical Cancer[J].Western Journal of Traditional Chinese Medicine,2021,34(06):103-106.[doi:10.12174/j.issn.2096-9600.2021.06.25]
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放射疗法配合黄药子汤保留灌肠治疗晚期宫颈癌临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年06期
页码:
103-106
栏目:
衷中参西
出版日期:
2021-06-15

文章信息/Info

Title:
Clinical Observation of Radiotherapy Combined with Retention Enema with Huangyaozi Decoction in the Treatment of Advanced Cervical Cancer
作者:
邓歌
天水市第一人民医院，甘肃 天水 741000
Author(s):
DENG Ge
Tianshui City the First People′s Hospital, Tianshui 741000, China
关键词:
宫颈癌; 晚期; 放射治疗; 黄药子汤剂; 保留灌肠; 扶正补虚
Keywords:
cervical cancer;  advanced; radiotherapy; decoction; retention enema; enhancing healthy and tonifying deficiency
分类号:
R737.3
DOI:
10.12174/j.issn.2096-9600.2021.06.25
摘要:
目的观察放射疗法（简称放疗）配合黄药子汤保留灌肠治疗晚期宫颈癌的临床疗效。 方法将宫颈癌患者（Ⅱb以上）86例，随机分为对照组与观察组，每组43例。对照组予以放疗，观察组在放疗的同时配合黄药子汤保留灌肠。观察两组癌灶变化、临床症状改善情况、生存质量、白介素1（interleukin-1，IL-1）、自然杀伤细胞（natural killer cell，NK）、肿瘤坏死因子（tumor necrosis factor，TNF）活性及不良反应发生率。 结果观察组癌灶、临床症状改善及生存质量均优于对照组（P＜0.05）；不良反应发生率显著低于对照组（P＜0.05）；治疗后观察组IL-1、NK细胞、TNF活性与对照组比较，差异有统计学意义（P＜0.05）。 结论放疗配合黄药子汤剂保留灌肠治疗晚期宫颈癌患者，能有效抑制或延缓肿瘤进程，改善患者临床症状，同时还能有效预防和修复放疗的不良反应。
Abstract:
ObjectiveTo observe clinical effects of radiotherapy and retention enema with Huangyaozi decoction in treating advanced cervical cancer. MethodsAll 86 patients (stage Ⅱb above) were randomly allocated to the control group and the observation group, 43 cases in each group. The control group accepted radiotherapy, and the observation group radiotherapy and Huangyaozi decoction retention enema. To observe the changes of tumor focus, the improvements of clinical symptoms, quality of life, the activity of IL-1, NK cells and TNF, and the incidence of adverse reaction in both groups. ResultsThe observation group was superior to the control group in tumor focus, the improvements of clinical symptoms and quality of life (P<0.05); lower than the control group in the incidence of adverse reaction notably (P<0.05); the difference was statistically significant when the activity of IL-1, NK cells and TNF of the observation group were compared with those of the control group after treating (P<0.05). ConclusionRadiotherapy and Huangyaozi decoction retention enema in treating advanced cervical cancer could effectively inhibit or delay the progression of tumor, improve clinical symptoms of the patients, simultaneously effectively prevent and improve adverse reaction induced by radiotherapy.

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备注/Memo

备注/Memo:
邓歌（1986—），女，主管技师。研究方法：肿瘤疾病的放射治疗与中西医结合治疗。
更新日期/Last Update: 2021-06-15