[1]马欢欢,王晓晖,王晶,等.基于“肾藏精生髓主骨”理论探讨中医药介导miRNA干预糖尿病性骨质疏松症研究进展[J].西部中医药,2025,38(08):105-109.[doi:10.12174/j.issn.2096-9600.2025.08.19]
　MA Huanhuan,WANG Xiaohui,WANG Jing,et al.Research Progress of TCM-mediated miRNA Intervention for Diabetic Osteoporosis Based on the Theory of "Kidney Storing Essence, Producing Marrow and Governing Bone"[J].Western Journal of Traditional Chinese Medicine,2025,38(08):105-109.[doi:10.12174/j.issn.2096-9600.2025.08.19]
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基于“肾藏精生髓主骨”理论探讨中医药介导miRNA干预糖尿病性骨质疏松症研究进展

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年08期
页码:
105-109
栏目:
研究进展
出版日期:
2025-08-15

文章信息/Info

Title:
Research Progress of TCM-mediated miRNA Intervention for Diabetic Osteoporosis Based on the Theory of "Kidney Storing Essence, Producing Marrow and Governing Bone"
作者:
马欢欢1, 王晓晖2, 王晶1, 王亚萍1, 马桃梅1, 韩世杰1
1.甘肃中医药大学，甘肃 兰州 730030
2.甘肃省中医药研究院，甘肃 兰州 730050
Author(s):
MA Huanhuan1, WANG Xiaohui2, WANG Jing1, WANG Yaping1, MA Taomei1, HAN Shijie1
1.Gansu University of Chinese Medicine, Lanzhou 730030, China
2.Gansu Provincial Academy of Chinese Medicine, Lanzhou 730050, China
关键词:
骨质疏松症; 糖尿病性; 肾藏精生髓主骨; 微小核糖核酸; 中医药
Keywords:
osteoporosis;  diabetic; kidney storing essence;  producing marrow and governing bone; microRNA; TCM
分类号:
R274.9
DOI:
10.12174/j.issn.2096-9600.2025.08.19
文献标志码:
A
摘要:
以“肾藏精生髓主骨”理论为前提，结合微小核糖核酸（microRNA，miRNA）在骨代谢中发挥的调节作用，探讨中医药介导miRNA在糖尿病性骨质疏松症（diabetic osteoporosis，DOP）中对成骨细胞的调控作用及其机制，以寻找有效的治疗靶点，为治疗DOP提供研究思路与治疗策略。
Abstract:
The paper discusses the regulatory effects of TCM-mediated miRNA on the osteoblasts in the treatment of DOP and the relevant mechanism based on the theory of "kidney storing essence, producing marrow and governing bone", in combination with the regulatory role of miRNA played in bone metabolism, so as to find out the effective therapeutic targets, which could provide research idea and therapeutic strategy for the therapy of DOP.

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备注/Memo

备注/Memo:
马欢欢（1994—），女，硕士学位，医师。研究方向：中西医结合防治内分泌及代谢性疾病。甘肃省科技重点研发计划项目（21YF5FA022）。
更新日期/Last Update: 2025-08-15