[1]刘馨,戴国华,高武霖.冠心病稳定型心绞痛中医证候及特异性症状的文献调查研究[J].西部中医药,2026,39(02):78-83.[doi:10.12174/j.issn.2096-9600.2026.02.16]
　LIU Xin,DAI Guohua,GAO Wulin.Literature Review on TCM Syndromes and Specific Symptoms of Stable Angina Pectoris of Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2026,39(02):78-83.[doi:10.12174/j.issn.2096-9600.2026.02.16]
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冠心病稳定型心绞痛中医证候及特异性症状的文献调查研究()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年02期
页码:
78-83
栏目:
二次研究
出版日期:
2026-02-15

文章信息/Info

Title:
Literature Review on TCM Syndromes and Specific Symptoms of Stable Angina Pectoris of Coronary Heart Disease
作者:
刘馨1, 戴国华2, 高武霖2
1.山东中医药大学第一临床医学院，山东 济南 250355
2.山东中医药大学附属医院，山东 济南 250011
Author(s):
LIU Xin1, DAI Guohua2, GAO Wulin2
1.First Clinical Medical School, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
2.Affiliated Hospital to Shandong University of Traditional Chinese Medicine, Jinan 250011, China
关键词:
稳定型心绞痛; 冠心病; 数字化研究; 示范性证候; 特异性症状; 主成分分析; 贝叶斯网络
Keywords:
stable angina pectoris;  coronary heart disease; digital research; exemplary syndromes; specific symptoms; principal component analysis; Bayesian network analysis
分类号:
R259
DOI:
10.12174/j.issn.2096-9600.2026.02.16
文献标志码:
A
摘要:
目的分析冠心病稳定型心绞痛（stable angina pectoris，SAP）中医证候及其特异性症状，为冠心病SAP中医辨证论治能力提升数字化研究示范性证候的专家访谈及德尔菲调查提供依据。 方法检索中国知网（CNKI）、万方、维普、中国生物医学文献数据库（CBM）中有关SAP证候研究的相关文献。检索时限为自建库至2020年12月31日。根据纳入、排除标准对文献进行筛选，分别提取文献中的中医证候及症状信息，利用Excel构建数据库并对证候及高频症状进行统计描述，运用SPSS Modeler18.0对高频症状信息进行主成分分析及贝叶斯网络分析。 结果共纳入文献684篇，涉及证候30种，频次排名前5位的复合证候分别为气虚血瘀证、痰阻血瘀证、心血瘀阻证、痰浊内阻证、气滞血瘀证；涉及基本证候9种，血瘀证、气虚证及痰浊证占比较高；涉及症状106种，高频症状包括胸痛、胸闷、脉涩、心悸及舌质紫等。高频症状主成分分析共提取11个主成分，大致分为血瘀证、气虚证、痰浊证及气滞证；通过贝叶斯公式推测出脉涩在SAP血瘀证诊断中起决定性作用，其次是胸部刺痛和舌有瘀斑瘀点；身倦在气虚证诊断中起决定性作用，其次是脉沉和乏力；苔腻在痰浊证诊断中起决定性作用，其次是舌体胖大和脉滑。 结论初步推断出血瘀证、气虚证及痰浊证的基本症状组成，明确高频症状对各基本证候的贡献度及基本证候的特异性症状，可为后续进一步研究SAP中医辨证论治能力提升数字化研究示范性证候提供一定依据。
Abstract:
ObjectiveThis study aims to provide a basis for expert interviews and a Delphi study, focusing on two objectives: (1) developing digital research-based exemplary syndromes, and (2) improving TCM syndrome differentiation and treatment for stable angina pectoris (SAP) in coronary heart disease (CHD). The basis will be established through an analysis of TCM syndrome patterns and the specific symptoms of CHD-related SAP. MethodsWe retrieved the literature on TCM syndrome research in SAP from CNKI, Wanfang, VIP and CBM. Search date range was between the time of database establishment and December 31sth, 2020. We performed literature screening according to the inclusion and exclusion criteria, extracted TCM syndrome and symptoms in the literature respectively, Excel was used to construct the database and conduct statistical description on the syndromes and high-frequency symptoms, SPSS Modeler 18.0 was applied to perform principal component analysis and Bayesian network analysis of high-frequency symptoms. ResultsAll 684 papers were included, involving 30 syndromes, the top five compound syndromes by frequency were Qi deficiency and blood stasis syndrome, phlegm obstruction and blood stagnation syndrome, heart blood stasis syndrome, internal phlegm-turbidity obstruction syndrome, Qi stagnation and blood stasis syndrome; nine syndromes were involved, blood stasis syndrome, Qi deficiency syndrome and phlegm-turbidity syndrome represented a high percentage; 106 symptoms were included, high-frequency symptoms covered chest pain, chest stuffiness, rough pulse, palpitations and purple tongue body. Principal component analysis of high-frequency symptoms yielded 11 principal components, roughly containing blood stasis syndrome, Qi deficiency syndrome, phlegm-turbidity syndrome and Qi stagnation syndrome; Bayesian inference suggests that the rough pulse plays a decisive role in diagnosing the blood stasis syndrome in SAP, stabbing pain in the chest, and petechiae or ecchymosis on the tongue are the next; lassitude is a critical determinant for the diagnosis of Qi deficiency pattern, deep pulse and fatigue are the next; greasy tongue is pivotal in identifying phlegm-turbidity syndrome, swollen tongue body and slippery pulse are the next. ConclusionWe initially assess the compositions of basic symptoms of blood stasis syndrome, Qi deficiency syndrome and phlegm-turbidity syndrome, confirm the contribution of high-frequency symptoms to each basic syndromes and the specific symptoms of basic syndromes, which could provide a basis for a follow-up study on digital research-based exemplary syndromes for advancing TCM syndrome differentiation and treatment of SAP.

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备注/Memo

备注/Memo:
国家重点研发项目（2019YFC1710400，2019YFC1710401）。刘馨（1994—），女，硕士学位。研究方向：心血管疾病的临床及循证医学研究。
更新日期/Last Update: 2026-02-15