[1]刘菡,张耀圣,商建伟.王沛教授运用猪苓-茯苓药对规律分析[J].西部中医药,2026,39(03):92-96.[doi:10.12174/j.issn.2096-9600.2026.03.18]
　LIU Han,ZHANG Yaosheng,SHANG Jianwei.Pattern Analysis of Professor Wang Pei?s Application of Herbal Pair Zhuling-Fuling[J].Western Journal of Traditional Chinese Medicine,2026,39(03):92-96.[doi:10.12174/j.issn.2096-9600.2026.03.18]
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王沛教授运用猪苓-茯苓药对规律分析()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年03期
页码:
92-96
栏目:
二次研究
出版日期:
2026-03-15

文章信息/Info

Title:
Pattern Analysis of Professor Wang Pei?s Application of Herbal Pair Zhuling-Fuling
作者:
刘菡, 张耀圣, 商建伟
北京中医药大学东直门医院，北京 100700
Author(s):
LIU Han, ZHANG Yaosheng, SHANG Jianwei
Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China
关键词:
猪苓-茯苓; 药对; 数据挖掘; 定量内容分析; 王沛
Keywords:
herbal pair; data mining; quantitative content analysis
分类号:
R249.2
DOI:
10.12174/j.issn.2096-9600.2026.03.18
文献标志码:
A
摘要:
目的运用数据挖掘和定量内容分析方法，挖掘王沛教授运用猪苓-茯苓药对规律和学术思想。 方法整理王沛教授近三十年医案，提取疾病处方数据，建立处方数据库。统计所有处方中猪苓-茯苓药对使用频次，计算其在不同疾病处方中的使用率；对猪苓-茯苓药对所在处方进行药物共现频次分析，选取共现关系较强的药物进行共现网络分析及聚类分析。 结果1）在处方数≥20首的疾病中，猪苓-茯苓药对的处方使用率均在30%以上，不同疾病间存在差异，消化系统肿瘤类疾病使用率较高。2）猪苓-茯苓药对与多种药物共现，共现频次较高的药物有生黄芪、炙黄芪、丹参、女贞子、夏枯草等。3）共现网络分析显示，猪苓-茯苓药对与生黄芪、炙黄芪、女贞子、何首乌、补骨脂、赤芍、白芍、丹参、夏枯草等药物呈现更密切的共现关系。4）聚类分析显示，猪苓-茯苓药对与女贞子、旱莲草、紫草、牡丹皮、生地黄、石斛归为一类。 结论1）猪苓-茯苓药对是王沛教授的常用配伍。2）猪苓-茯苓常与利水渗湿药配伍，以祛痰利湿。3）猪苓-茯苓常与益气健脾药配伍，以淡渗泄浊。4）猪苓-茯苓常与补肾益阴药配伍，体现通补兼施的用药原则。
Abstract:
ObjectiveTo unearth professor Wang Pei’s application pattern of herbal pair Zhuling (Polyporus)-Fuling [Poria cocos (Schw.) Wol] and his academic thinking using data mining and quantitative content analysis. MethodsThe database of prescriptions was established by collecting professor Wang’s medical cases in the last 30 years and extracting the prescription data for diseases. The usage frequency of herbal pair Zhuling-fuling was tallied across all prescriptions, and its utilization rate in prescriptions for different diseases was calculated; co-occurrence frequency analysis of Zhuling-fuling was performed on the herbs within prescriptions containing the Zhuling-Fuling herb pair, herbs with strong co-occurrence relationships were then selected for co-occurrence network analysis and cluster analysis. Results1) among the diseases with at least 20 prescriptions, the utilization rate of the prescription containing Zhuling-fuling reached higher than 30%, and the differences existed between different diseases, and the utilization rate was higher for digestive tract tumor diseases. 2) herbal pair Zhuling-fuling co-occurred with many kinds of herbs, the herbs with higher co-occurrence frequency covered Huangqi (Astragali radix), Zhihuɑngqi (Astragali radix praeparata cum melle), Danshen (Salviae miltiorrhizae radix et rhizoma), Nüzhenzi(Ligustri lucidi fructus) and Xiakucao (Prunellae spica). 3) Co-occurrence network analysis revealed that the Zhuling-Fuling herb pair presented stronger co-occurrence relationship with Huangqi, Zhihuɑngqi, Nüzhenzi, Heshouwu (Polygoni multiflori radix), Buguzhi (Psoraleae fructus), Chishao (Paeoniae radix Rubra), Baishao (Paeoniae radix alba), Danshen (Salviae miltiorrhizae radix et rhizoma) and Xiakucao (Prunellae spica). 4) Cluster analysis demonstrated that Zhuling-fuling, and Nüzhenzi, Mohanlian (Ecliptae herba), Zicao (Arnebiae radix), Mudanpi (Moutan cortex), Dihuang(Rehmanniae radix) and Shihu(Dendrobii caulis) were classified into the same group. Conclusion1)The Zhuling-Fuling herb pair is a commonly used combination by professor Wang Pei. 2)The Zhuling-Fuling herb pair is frequently combined with diuretic and dampness-resolving herbs in order to eliminate phlegm and dampness. 3)The Zhuling-Fuling herb pair is frequently combined with benefiting-Qi invigorating-spleen herbs so as to induce diuresis and eliminate turbidity. 4)The Zhuling-Fuling herb pair is often used with the herbs of invigorating kidney and nourishing Yin, embodying the medication principles of combined unblocking and tonifying.

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备注/Memo

备注/Memo:
中央高水平中医医院临床科研业务费资助（编号DZMG-LJRC0009）。刘菡（1992—），女，博士学位，医师。研究方向：中医药防治泌尿外科疾病。
更新日期/Last Update: 2026-03-15