[1]席彩霞,杨国泉,苏安平,等.贞芪益气胶囊联合 GP 方案治疗晚期非小细胞肺癌的临床研究[J].西部中医药,2014,27(09):4-7.
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贞芪益气胶囊联合 GP 方案治疗晚期非小细胞肺癌的临床研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年09期
页码:
4-7
栏目:
论著·临床论著
出版日期:
2014-09-15

文章信息/Info

作者:
席彩霞杨国泉苏安平李正国陶文学刘雪梅
甘肃省武威肿瘤医院呼吸科,甘肃 武威 733000
关键词:
非小细胞肺癌贞芪益气胶囊化疗
分类号:
R734.2
摘要:
目的:观察贞芪益气胶囊联合GP方案(吉西他滨+顺铂)治疗晚期非小细胞肺癌的近期临床疗效、毒性反应及其对无进展生存期的影响。方法:将晚期非小细胞肺癌患者67例随机分为治疗组34例和对照组33例。治疗组应用贞芪益气胶囊联合GP方案治疗,对照组单用GP方案治疗,每21天为1个周期,治疗4周期后观察疗效。结果:治疗组有效率和疾病控制率分别为47.1%、79.4%,高于对照组的39.4%、63.6%,但无统计学意义(P>0.05);治疗组患者生活质量及症状改善情况优于对照组,2组比较差异具有统计学意义(P<0.05);治疗组白细胞减少及恶心、呕吐例数明显低于对照组(P<0.05);2组无进展生存期比较,差异具有统计学意义(P<0.05)。结论:贞芪益气胶囊联合GP方案能改善晚期非小细胞肺癌患者症状,减轻化疗的毒性反应,提高患者生存质量,可延长患者的无进展生存期。

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备注/Memo

备注/Memo:
作者简介:席彩霞(1978—),女,硕士学位,主治医师。研究方向:肺癌的诊治。
更新日期/Last Update: 2014-09-15