[1]李红霞,万国蕊,徐静,等.三花益肾汤治疗子宫内膜异位症临床观察[J].西部中医药,2015,28(01):7-10.
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三花益肾汤治疗子宫内膜异位症临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年01期
页码:
7-10
栏目:
出版日期:
2015-01-15

文章信息/Info

文章编号:
1004-6852(2015)01-0007-04
作者:
李红霞，万国蕊，徐静，刘艳，吕红玉，指导：刘召
白银市平川区水泉中心卫生院妇产科，甘肃 白银 730916
关键词:
子宫内膜异位症; 孕三烯酮; 性腺激素; 血清炎性细胞因子; 三花益肾汤
分类号:
R711.71
摘要:
目的：观察三花益肾汤治疗子宫内膜异位症(EM)的临床疗效，探讨其作用机理。方法：将EM患者60例随机分为治疗组、对照组各30例，治疗组予三花益肾汤治疗，1剂/d，对照组予孕三烯酮治疗，2.5 mg/次，2次/周，连续治疗3个月后比较2组临床总有效率、主观症状改善情况、子宫体积及盆腔包块变化情况、血清糖链抗原125(CA125)、雌二醇(E2)、催乳素(PRL)、孕酮(P)、血管内皮生长因子(VEGF)、肿瘤坏死因子(TNF-α)、白细胞介素6(IL－6)等变化情况。结果：总有效率治疗组为90.0%，对照组为86.7%，2组比较差异无统计学意义(P＞0.05)；2组患者治疗后CA125、E2、PRL、VEGF、TNF-α、IL－6含量较治疗前明显下降，P水平有所上升；主观症状明显改善；盆腔包块较治疗前缩小，且治疗组较对照组缩小明显(P＜0.05)，子宫体积大小治疗前后无变化(P＞0.05)。结论：三花益肾汤能抑制异位内膜播散种植而消除病灶，缓解疼痛，提高受孕率，减少复发。

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备注/Memo

备注/Memo:
作者简介：李红霞(1977—)，女，主治医师。研究方向：女性内分泌疾病的中西医结合诊治。
更新日期/Last Update: 2015-01-15