[1]王小龙,亓咏梅△.基于复杂熵聚类的152张失眠症中药处方用药规律分析[J].西部中医药,2019,32(06):50-53.
　WANG Xiaolong,QI Yongmei.Medication Rules of 152 Herbal Prescriptions for Insomnia Based on Complex Entropy Clustering[J].Western Journal of Traditional Chinese Medicine,2019,32(06):50-53.
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基于复杂熵聚类的152张失眠症中药处方用药规律分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年06期
页码:
50-53
栏目:
出版日期:
2019-06-15

文章信息/Info

Title:
Medication Rules of 152 Herbal Prescriptions for Insomnia Based on Complex Entropy Clustering
文章编号:
1004-6852(2019)06-0050-04
作者:
王小龙，亓咏梅△
阜阳市中医医院药剂科，江苏 阜阳 236000
Author(s):
WANG Xiaolong, QI Yongmei△
Department of Pharmacy, Fuyang City TCM Hospital, Fuyang 236000, China
关键词:
失眠; 处方; 配伍规律
Keywords:
insomnia;  prescription;  compatibility rules
分类号:
R256.23
文献标志码:
A
摘要:
目的：对失眠症处方用药规律进行分析，以期探明临床治疗失眠的组方配伍思路，提高临床疗效。方法：随机抽取2016年6月至2017年2月门诊、住院患者治疗失眠、不寐的中医处方，经筛选，共纳入处方152张。将152张处方录入中医传承辅助平台(V2.5)软件进行统计分析。结果：酸枣仁、首乌藤、茯神、当归、合欢皮为治疗失眠的核心药物，失眠药物以甘平、苦温为主，主入肝、心、脾、肾经。龙骨-牡蛎，合欢皮-首乌藤，五味子-酸枣仁，远志-酸枣仁，当归-酸枣仁，均是治疗失眠的常用药对，配伍关系较为密切。结论：从安神、清热、养阴、和营、益气、补血、活血、祛痰着手，以及从热、瘀、痰、气、血论治，为治疗失眠症开拓了新的组方思路。
Abstract:
Objective: To analyze the medication rules of the prescriptions for insomnia in the wish of exploring prescription compatibility thinking of treating insomnia and raising clinical effects. Methods: Herbal prescriptions for insomnia in the outpatients and inpatient were randomly chosen from June, 2016 to February, 2017, a total of 152 prescriptions were included after screening, and they were typed into Traditional Chinese Medicine Inheritance Support System (TCMISS v2.5) and analyzed statistically. Results: Suanzaoren (ziziphispinosaesemen), Shouwuteng (polygoni multiflori caulis), Fushen [Poria cocos (Schw.) Wolf ], Danggui (angelicae sinensis radix) and Hehuanpi (alibiziae cortex) were the core drugs of treating insomnia, the drugs of treating insomnia were of sweet taste and neural nature, bitter taste and warm nature mainly, and they entered the meridians of liver, heart, spleen and kidney. Longgu [OsDraconis(FossiliaOssiaMastodi)]-Muli (ostreae concha), Hehuanpi-Shouwuteng, Wuweizi(schisandrae chinensis fructus)-Suanzaoren, Yuanzhi (polygalae radix)-Suanzaoren, Danggui-Suanzaoren were the commonly-used drug pairs of treating insomnia, the compatibility between them were closer. Conclusion: It could provide a new thinking for the prescriptions of treating insomnia by tranquilizing, clearing heat, nourishing Yin, harmonizing Yin, invigorating Qi, nourishing blood, promoting blood circulation and eliminating phlegm based on heat, stasis, phlegm, Qi and blood.

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备注/Memo

备注/Memo:
收稿日期：2018-10-15作者简介：王小龙(1989—)，男，硕士学位，主管中药师。研究方向：中药临床药学研究。△通讯作者：亓咏梅(19—)，女，主管药师。研究方向：临床药学研究。
更新日期/Last Update: 2019-06-15