[1]吕安林.食管癌术后中药辅助治疗42例疗效观察[J].西部中医药,2013,26(08):92-93.
　LV Anlin.Postoperative Adjuvant Treatment for 42 Patients after the Surgery of Esophageal Cancer with TCM[J].Western Journal of Traditional Chinese Medicine,2013,26(08):92-93.
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食管癌术后中药辅助治疗42例疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年08期
页码:
92-93
栏目:
出版日期:
2013-08-15

文章信息/Info

Title:
Postoperative Adjuvant Treatment for 42 Patients after the Surgery of Esophageal Cancer with TCM
文章编号:
1004-6852(2013)08-0092-02
作者:
吕安林
平凉市人民医院，甘肃 平凉 744000
Author(s):
LV Anlin
Pingliang Municipal People′s Hospital, Pingliang 744000, China
关键词:
食管癌术后; 中药; 辅助治疗
Keywords:
after the surgery of esophageal cancer;  TCM;  adjuvant treatment
分类号:
R735
文献标志码:
B
摘要:
目的：观察食管癌术后使用中药辅助治疗的临床疗效；方法：将72例食管癌术后患者分为观察组42例、对照组30例，2组患者术后均接受化疗，观察组在此基础上予中药内服，2组共治疗2个疗程。治疗期间每周进行一次卡氏评分以评价其生活质量改善情况，并在治疗前后检测静脉血中T淋巴细胞亚群和免疫球蛋白含量变化情况，以评估患者免疫功能情况。结果：卡氏评分结果显示观察组病情改善31例，稳定11例，未见恶化病例，对照组病情改善17例，稳定12例，恶化1例；经卡方检验χ2=11.1669，P=0.0109。2组T淋巴细胞亚群CD3+、CD4+、CD8+变化经t检验可得t=2.3.32，P=0.0242；2组免疫球蛋白IgA、IgG、IgM变化经t检验可得t=2.5614，P=0.0126，2组比较差异具有统计学意义。结论：中药汤剂能提高食管癌术后患者生活质量与免疫功能，可作为辅助治疗在临床上推广使用。
Abstract:
Objective: To observe curative effects of postoperative adjuvant treatment for the patients after the surgery of esophageal cancer with TCM. Method: Seventy-two patients were divided into 42 cases of the observation group and 30 cases of the control group, both groups received chemotherapy, the observation group took herbs, both groups were treated for two courses of treatment. The improvements of life quality were evaluated during the treatment by Karnofsky's performance scale each week, the changes of immunoglobulin and T-lymphocyte subsets contents were detected before and after treating in the venous blood to assess immunologic function of the patients. Result: Karnofsky results revealed that there were 31 cases improved, 11 cases stable and no case deteriorated in the observation group, 17 cases improved, 12 cases stable and one case deteriorated in the control group; detected with chi-square test χ2=11.1669, P=0.0109. The changes of T-lymphocyte subsets including CD3+, CD4+ and CD8+ showed that t=2.332, P=0.0242 by T test; the changes of immunoglobulin including IgA, IgG and IgM were detected with T test and the results showed t=2.5614, P=0.0126, the difference had statistical meaning. Conclusion: TCM decoction could improve life quality and immunologic function of the patients after the surgery of esophageal cancer, which could be spread as adjuvant treatment.

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备注/Memo

备注/Memo:
收稿日期：2012-12-04 作者简介：吕安林(1965—)，男，副主任医师。研究方向：胸外科疾病的诊治。
更新日期/Last Update: 2013-08-15