[1]徐思羽,顾秀琰,张琳.HPLC测定杜仲腰痛浓缩丸中阿魏酸含量[J].西部中医药,2014,27(02):29-30.
　XU Siyu,GU Xiuyan,ZHANG Lin.Determination of Ferulic Acid in DuZhong YaoTong Concentrated Pills by HPLC[J].Western Journal of Traditional Chinese Medicine,2014,27(02):29-30.
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HPLC测定杜仲腰痛浓缩丸中阿魏酸含量
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年02期
页码:
29-30
栏目:
出版日期:
2014-02-15

文章信息/Info

Title:
Determination of Ferulic Acid in DuZhong YaoTong Concentrated Pills by HPLC
文章编号:
1004-6852(2014)02-0029-02
作者:
徐思羽，顾秀琰，张琳
甘肃省中医院，甘肃 兰州 730050
Author(s):
XU Siyu, GU Xiuyan, ZHANG Lin
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
杜仲腰痛浓缩丸; 阿魏酸; 高效液相色谱
Keywords:
DuZhong YaoTong concentrated pills;  ferulic acid;  HPLC
分类号:
R282.5
文献标志码:
A
摘要:
目的：采用高效液相色谱法测定杜仲腰痛浓缩丸中阿魏酸含量。方法：色谱柱：Symmetry C18柱(5 μm，4.6 mm×250 mm)；流动相：乙腈-0.085%磷酸水溶液(17∶83)(V/V)；流速：1.0 mL/min；检测波长：316 nm。结果：阿魏酸在2.02～20.02 mg/L之间线性关系良好( r=0.999 7，n=6)，平均加样回收率为98.09%，RSD为1.02%。结论：本法操作简便，结果准确，可用于杜仲腰痛浓缩丸的质量控制。
Abstract:
Objective: To determine the contents of ferulic acid in DuZhong YaoTong concentrated pills by HPLC. Methods: Chromatographic column: Symmetry C18 column (5 μm, 4.6 mm×250 mm); mobile phase: acetonitrile-0.085% phosphoric acid solution(17:83)(V/V); the flow rate: 1.0mL/min; detection wavelength: 316nm. Results: Ferulic acid showed better linear relationship in the range between 2.02 and 20.02 mg/L(r=0.999 7, n=6), average recovery was 98.09%, RSD was 1.02%. Conclusion: The method, simple and accurate, could be used for quality control of DuZhong YaoTong concentrated pills.

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备注/Memo

备注/Memo:
收稿日期：2013-05-13作者简介：徐思羽(1974—)，女，主管药师。研究方向：药学和制剂研究。
更新日期/Last Update: 2014-02-15