[1]胡春娜.老年晚期结直肠癌患者术后早期中医辨证分型及预后标志物表达情况分析[J].西部中医药,2017,30(10):61-63.
　HU Chunna.The Investigation into Syndrome Differentiation and Classfication of the Elderly Patients after the Surgery of Terminal Rectal Cancer at Early Stage and the Analysis on the Expressions of Prognostic Markers[J].Western Journal of Traditional Chinese Medicine,2017,30(10):61-63.
点击复制

老年晚期结直肠癌患者术后早期中医辨证分型及预后标志物表达情况分析()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年10期
页码:
61-63
栏目:
出版日期:
2017-10-15

文章信息/Info

Title:
The Investigation into Syndrome Differentiation and Classfication of the Elderly Patients after the Surgery of Terminal Rectal Cancer at Early Stage and the Analysis on the Expressions of Prognostic Markers
文章编号:
1004-6852(2017)10-0061-03
作者:
胡春娜
唐山市中医院肛肠一科，河北 唐山 063000
Author(s):
HU Chunna
The First Anorectal Department, Tangshang Municipality TCM Hospital, Tangshan 063000, China
关键词:
结直肠癌; 老年; 中医辨证分型; 预后
Keywords:
colorectal cancer;  the elderly;  syndrome differentiation and classification;  the prognosis
分类号:
R735.3
文献标志码:
A
摘要:
目的：分析老年晚期结直肠癌患者术后早期中医辨证分型情况及预后标志物表达情况。方法：选择2014年1月至2016年1月就诊的80例老年晚期结直肠癌患者，对其术后早期症状进行中医辨证分型，同时分析不同证型患者术后预后标志物表达情况。结果：老年结直肠癌患者术后早期中医证型中，湿热瘀毒型及肝肾阴虚型分别占30%及31.25%，明显高于其他3种证型，差异有统计学意义(P＜0.05)；湿热瘀毒型及肝肾阴虚型患者术后血清癌胚抗原(CEA)、糖类抗原125(CA125)水平及肿瘤特异性生长因子(TSGF)阳性表达率明显高于其他3种证型，差异有统计学意义(P＜0.05)；脾肾两虚型及肝肾阴虚型患者Karnofsky评分≤70分比例明显高于其他3种证型，差异有统计学意义(P＜0.05)。结论：湿热瘀毒及肝肾功能的变化预示结直肠癌患者预后不良。
Abstract:
Objective: To analyze the conditions of syndrome differentiation and classification of the elderly patients after the surgery of terminal colo rectal cancer at the early stage and the expressions of prognostic markers. Methods: Eighty elderly patients suffering terminal colo rectal cancer who visited from January, 2014 to January, 2016 were chosen, their early symptoms after the operation were differentiated, meanwhile, the expressions of prognostic markers of the patients in different patterns after the operation were analyzed. Results: The patients of dampness-heat and stagnant toxin pattern and liver-kidney Yin-deficiency pattern occupied 30% and 31.25% respectively, obviously higher than other three patterns, and the difference showed statistical meaning (P＜0.05); the levels of CEA and CA125, the positive expression rate of TSGF of the patients in dampness-heat and stagnant toxin pattern and liver-kidney Yin-deficiency pattern were notably higher than these of the patients in other three patterns, and the difference demonstrated statistical meaning (P＜0.05); Karnofsky scales of the patients in spleen-kidney dual deficiency pattern and liver-kidney Yin-deficiency pattern less than 70 points, and they were higher than these of the patients in other three patterns, and the difference demonstrated statistical meaning (P＜0.05). Conclusion: The patterns of dampness-heat and stagnant toxin and the changes of liver and renal functions indicate the poor prognosis of the patients suffering rectal cancer.

相似文献/References:

[1]马哲河.滋阴舒肝法治疗老年患者失眠49例[J].西部中医药,2014,27(06):80.
　MA Zhehe.Treating 49 Senile Patients with Insomnia by Yin-nourishing Liver-soothing Method[J].Western Journal of Traditional Chinese Medicine,2014,27(10):80.
[2]李生.DHS内固定联合中药治疗中老年股骨粗隆间骨折的临床疗效[J].西部中医药,2013,26(11):96.
　LI Sheng.Therapeutic Effects of Internal Fixation with DHS and TCM for Senile Patients with Intertrochanter Fracture of Femur[J].Western Journal of Traditional Chinese Medicine,2013,26(10):96.
[3]王鸿燕.丹参酮注射液治疗老年不稳定型心绞痛(心血瘀阻证)50例临床观察[J].西部中医药,2013,26(05):5.
　WANG Hongyan.Observation on DanShenTong Injection in Treating 50 Cases of Senile Unstable Angina Pectoris of Heart Blood Stagnation-obstruction Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(10):5.
[4]姜岩.探讨介入球囊扩张治疗老年糖尿病足的护理措施[J].西部中医药,2014,27(07):121.
　JIANG Yan.Nursing Intervention for Senile Patients with Diabetic Foot Treated by Balloon Dilatation[J].Western Journal of Traditional Chinese Medicine,2014,27(10):121.
[5]张艳.老年溃疡病出血患者内镜下止血效果的护理分析[J].西部中医药,2015,28(08):150.
[6]宋宗梅,郭雪梅.护理干预在预防老年下肢骨折术后深静脉血栓形成中的作用[J].西部中医药,2015,28(10):130.
[7]雷琛,杨婕,蒋理立,等.结直肠癌患者术前疾病不确定感的影响因素及治疗性沟通护理的意义[J].西部中医药,2018,31(05):121.
　LEI Chen,YANG Jie,JIANG Lili,et al.On Influencing Factors of Illness Uncertainty of the Patients before the Surgery of Colorectal Cancer and the Meaning of Therapeutic Communication Nursing[J].Western Journal of Traditional Chinese Medicine,2018,31(10):121.
[8]宫姣,李艳,郝庆.泽泻醇-B-乙酸酯对结直肠癌HCT116细胞增殖和周期的影响[J].西部中医药,2017,30(03):22.
　GONG Jiao,LI Yan,HAO Qing.Effect of Alisol-B-acetate on Proliferation and Cycle of Colorectal Cancer Cell Line HCT116[J].Western Journal of Traditional Chinese Medicine,2017,30(10):22.
[9]聂晶,郑超,李馨△.参麦注射液联合依那普利治疗老年高血压伴冠心病不稳定型心绞痛疗效观察[J].西部中医药,2017,30(11):93.
　NIE Jing,ZHENG Chao,LI Xin.Study on Clinical Effects of ShenMai Injection Combined with Enalapril in the Treatment of Senile Hypertension Complicated with CHD Unstable Angina Pectoris[J].Western Journal of Traditional Chinese Medicine,2017,30(10):93.
[10]王颢,潘剑△.仙灵骨葆胶囊治疗老年骨质疏松性腰椎压缩骨折40例[J].西部中医药,2017,30(08):89.
　WANG Hao,PAN Jian.XianLing GuBao Capsules in Treating 40 Cases of Senile Osteoporotic Compression Fracture of Lumbar Vertebra[J].Western Journal of Traditional Chinese Medicine,2017,30(10):89.
[11]李威,林珠,刘晓燕,等.穴位按压对老年转移性结直肠癌维持治疗患者癌因性疲乏的干预效果[J].西部中医药,2024,37(07):143.[doi:10.12174/j.issn.2096-9600.2024.07.34]
　LI Wei,LIN Zhu,LIU Xiaoyan,et al.Intervention Effect of Acupressure on Cancer-related Fatigue in Elderly Patients with Metastatic Colorectal Cancer Undergoing Maintenance Treatment[J].Western Journal of Traditional Chinese Medicine,2024,37(10):143.[doi:10.12174/j.issn.2096-9600.2024.07.34]

备注/Memo

备注/Memo:
收稿日期：2017-01-22 作者简介：胡春娜(1978—)，女，主管护师。研究方向：肛肠科疾病的临床护理。
更新日期/Last Update: 2017-10-15