[1]廖芳,王欢,谭天林,等.多指标综合评分法对强筋接骨胶囊提取工艺参数的优化研究[J].西部中医药,2018,31(06):27-30.
　LIAO Fang,WANG Huan,TAN Tianlin,et al.Study of Extraction Process Parameters Optimization of QiangJin JieGu Capsules by Multiple Indexes Comprehensive Scoring Method[J].Western Journal of Traditional Chinese Medicine,2018,31(06):27-30.
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多指标综合评分法对强筋接骨胶囊提取工艺参数的优化研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年06期
页码:
27-30
栏目:
出版日期:
2018-06-15

文章信息/Info

Title:
Study of Extraction Process Parameters Optimization of QiangJin JieGu Capsules by Multiple Indexes Comprehensive Scoring Method
文章编号:
1004-6852(2018)06-0027-04
作者:
廖芳1，王欢1，谭天林1，陈纬别1，马书军1，张丹2△
1 成都市新都区中医医院，四川 成都 610500； 2 西南医科大学
Author(s):
LIAO Fang1, WANG Huan1, TAN Tianlin1, CHEN Weibie1, MA Shujun1, ZHANG Dan2△
1 Xindu District TCM Hospital, Chengdu 610500, China; 2 Southwest Medical University
关键词:
柚皮苷; 阿魏酸; 医疗机构制剂; 提取工艺
Keywords:
naringin;  ferulic acid;  the preparation in medical institution;  extraction process
分类号:
R932
文献标志码:
A
摘要:
目的：对强筋接骨胶囊提取工艺参数进行优化，以提升该制剂的质量控制标准。方法：采用正交实验方法以出膏率、柚皮苷、阿魏酸含量测定等为评价指标，考察加水量、提取时间、提取次数对提取工艺的影响。结果：综合评分法显示，最佳提取工艺为加水6倍量，提取2次，每次提取60分钟。结论：该提取工艺稳定可行。
Abstract:
Objective: To raise the standard for quality control of the preparation by optimizing extraction process parameters of QiangJin JieGu capsules. Methods: Orthogonal test was performed, ointment rate, content determination of naringin and ferulic acid were chosen as the evaluating indexes, the influences of water addition, extraction time and extraction times on extraction process were investigated. Results: Comprehensive scoring method shows that the optimal extraction process was adding six times of water, extracting twice, extracting for 60 minutes each time. Conclusion: The extraction process is stable and feasible.

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备注/Memo

备注/Memo:
收稿日期：2017-08-11 *基金项目：四川省科技厅“科技支撑计划”课题(编号2014SZ0141)。 作者简介：廖芳(1975—)，女，硕士学位，副主任中药师。研究方向：中药制剂及工艺、中药制剂质量控制。 △通讯作者：张丹(1975—)，女，副教授。研究方向：中药新工艺、中药新剂型、中药炮制。
更新日期/Last Update: 2018-06-15