[1]周静,陈萍.寿胎丸联合阿司匹林及泼尼松治疗复发性流产41例[J].西部中医药,2018,31(06):88-90.
　ZHOU Jing,CHEN Ping.ShouTai Pills, Aspirin and Prednison in the Treatment for 41 Cases of Recurrent Spontaneous Abortion[J].Western Journal of Traditional Chinese Medicine,2018,31(06):88-90.
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寿胎丸联合阿司匹林及泼尼松治疗复发性流产41例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年06期
页码:
88-90
栏目:
出版日期:
2018-06-15

文章信息/Info

Title:
ShouTai Pills, Aspirin and Prednison in the Treatment for 41 Cases of Recurrent Spontaneous Abortion
文章编号:
1004-6852(2018)06-0088-03
作者:
周静,陈萍
河南中医药大学第一临床医学院，河南 郑州 450000
Author(s):
ZHOU Jing, CHEN Ping
The First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou 450000, China
关键词:
流产; 复发性; 寿胎丸; 阿司匹林
Keywords:
abortin;  recurrent;  ShouTai pills;  aspirin
分类号:
R714.21
文献标志码:
B
摘要:
目的：观察寿胎丸联合阿司匹林、泼尼松治疗复发性流产的临床疗效。方法：将82例患者随机分为观察组和对照组，每组41例。对照组采用阿司匹林、泼尼松治疗，观察组同时服用寿胎丸，每日1剂。连续服药超以往流产时间15天后停药。治疗后随访1年，观察2组临床疗效、不良反应及治疗前后凝血酶原时间(PT)、活化部分凝血活酶时间（APTT)，血浆纤维蛋白原（FIB）、D-二聚体(D-Dimer)表达水平。结果：总有效率观察组为85.37%，对照组为51.22%，2组比较差异有统计学意义(P＜0.05)。不良反应发生率观察组为7.32%，对照组为17.07%，2组比较差异有统计学意义(P＜0.05)。治疗后，PT、APTT水平2组比较，差异无统计学意义(P＞0.05)，FIB、D-Dimer指数2组比较，差异有统计学意义(P＜0.05)。结论：寿胎丸联合阿司匹林治疗复发性流产效果显著，安全性高，可有效提高患者保胎成功率。
Abstract:
Objective: To observe clinical effects of ShouTai pills, aspirin and prednison in treating recurrent spontaneous abortion (RSA). Methods: All 82 patients were randomly allocated to the observation group and the control group, 41 cases each group. The control group adopted aspirin and prednison, and the observation group took ShouTai pills simultaneously, one dose each day. The patients continued to take the medicine lasting longer than the previous abortion time and then stopped taking the medicine. In the follow-ups in one year after treating, the expressions of D-Dimer, plasma fibrinogen (FIB), activated partial thromboplastin time (APTT) and prothrombin time (PT) of the coagulation indexes before and after treating, adverse reaction and curative effects of both groups were observed. Results: Total effective rate of the observation group was 85.37%, higher than 51.22% of the control group, and the difference had statistical meaning (P＜0.05). The incidence of adverse reaction of the observation group was 7.32%, lower than 17.07% of the control group, and the difference showed statistical meaning (P＜0.05). The difference had no statistical meaning in the comparisons of PT, APTT and others between both groups after treating (P＞0.05), the difference was statistically significant in the comparisons of FIB and D-Dimer between both groups (P＜0.05). Conclusion: ShouTai pills, aspirin and prednison could gain notable effects in treating RSA with high safety, and the therapy could effectively raise the success rate of preventing miscarriage.

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备注/Memo

备注/Memo:
收稿日期：2017-12-11 作者简介：周静(1979—)，女，硕士学位，主治医师，讲师。研究方向：妊娠病的诊治。
更新日期/Last Update: 2018-06-15