[1]宋玉,姜晨.中药干预CKD血管钙化的研究进展[J].西部中医药,2020,33(03):150-155.[doi:10.12174/j.issn.1004-6852.2020.03.43]
　SONG Yu,JIANG Chen.Research Progress on Materia Medica in the Intervention of CKD Vascular Calcification[J].Western Journal of Traditional Chinese Medicine,2020,33(03):150-155.[doi:10.12174/j.issn.1004-6852.2020.03.43]
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中药干预CKD血管钙化的研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年03期
页码:
150-155
栏目:
出版日期:
2020-03-15

文章信息/Info

Title:
Research Progress on Materia Medica in the Intervention of CKD Vascular Calcification
文章编号:
1004-6852(2020)03-0150-06
作者:
宋玉，姜晨
天津中医药大学第一附属医院，天津 300381
Author(s):
SONG Yu, JIANG Chen△
First Teaching Hospital of Tianjin University of TCM, Tianjin 300381, China
关键词:
慢性肾脏病; 血管钙化; 中药单体; 中药复方; 综述
Keywords:
chronic kidney disease;  vascular calcification;  herbal monomer;  herbal compound;  review
分类号:
R692
DOI:
10.12174/j.issn.1004-6852.2020.03.43
摘要:
以中药单体、中药复方作为主要研究对象，对中药干预慢性肾脏病(chronic kidney disease，CKD)血管钙化的相关实验研究和临床研究做一综述，指出血管钙化作为心血管疾病(cardiovascular disease，CVD)风险等级中的最高级，一直是研究的重点及难点。在CKD研究领域中抑制血管钙化的进程被认为是控制疾病的关键因素，中药可通过调整钙磷代谢紊乱、抑制炎症反应、调节氧化应激等改善血管钙化程度、延缓血管钙化进展，对CKD血管钙化的干预作用已成为研究热点。
Abstract:
By taking herbal monomer, herbal compound as the main research objects, clinical study and the related experimental study on materia medica in the intervention of CKD vascular calcification were reviewed, it is pointed out that vascular calcification is the highest risk level of CVD, and it has been the keypoint and difficult part in the research, inhibiting vascular calcification progression is considered to be the key factor in disease control in the research field of CKD, intervention effects of materia medica on CKD vascular calcification have been research hotspot through adjusting the disorder of calcium and phosphorus metabolism, inhibiting inflammatory reaction, regulating oxidative stress to improve vascular calcification degree and delay its progression.

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备注/Memo

备注/Memo:
收稿日期：2019-04-06*基金项目：国家自然科学基金青年科学基金(81302920)。作者简介：宋玉(1994—)，女，在读硕士研究生。研究方向：肾脏病的中医治疗。△通讯作者：姜晨(1982—)，女，博士学位，硕士研究生导师，副主任医师。研究方向：肾脏病的中西医结合治疗。
更新日期/Last Update: 2020-03-15