[1]张平,王晓琳,马潇,等.当归道地产区岷县土壤中无机元素与岷当归药材质量相关性分析?[J].西部中医药,2021,34(11):65-72.[doi:10.12174/j.issn.2096-9600.2021.11.13]
　ZHANG Ping,WANG Xiaolin,MA Xiao,et al.The Correlations between the Quality of Mindanggui and the Organic Elements in Soil of Danggui Genuine Producing Areas Minxian[J].Western Journal of Traditional Chinese Medicine,2021,34(11):65-72.[doi:10.12174/j.issn.2096-9600.2021.11.13]
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当归道地产区岷县土壤中无机元素与岷当归药材质量相关性分析?
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年11期
页码:
65-72
栏目:
质量分析
出版日期:
2021-11-15

文章信息/Info

Title:
The Correlations between the Quality of Mindanggui and the Organic Elements in Soil of Danggui Genuine Producing Areas Minxian
作者:
张平1,2,3, 王晓琳4,5, 马潇1,2,3, 刘志荣1,2,3, 李冬华1,2,3, 宋平顺1,2,3, 杨平荣1,2,3
1.甘肃省药品检验研究院，甘肃 兰州 730070
2.甘肃省中藏药检验检测工程技术实验室
3.国家药品监督管理局中药材及饮片质量控制重点实验室
4.甘肃省中医院
5.甘肃省中医药研究院
Author(s):
ZHANG Ping1,2,3, WANG Xiaolin4,5, MA Xiao1,2,3, LIU Zhirong1,2,3, LI Donghua1,2,3, SONG Pingshun1,2,3, YANG Pingrong1,2,3
1.Gansu Institute for Drug Control, Lanzhou 730070, China
2.Gansu Engineering Technology Laboratory for Inspection and Testing of Chinese and Tibetan Medicine
3.Key Laboratory for Quality Control of Traditional Chinese Medicine and Decoction Pi
关键词:
当归; 岷县; 道地药材; 道地产区; 无机元素
Keywords:
county; genuine medicinal materials; genuine producing areas; inorganic elements
分类号:
R284
DOI:
10.12174/j.issn.2096-9600.2021.11.13
文献标志码:
A
摘要:
目的建立岷当归电感耦合等离子体质谱法（ICP-MS）元素检测方法，分析道地药材岷当归种植地土壤中无机元素对岷当归药材质量的影响。 方法采用ICP-MS法测定岷县不同产地20批岷当归药材和种植土壤中的无机元素含量，测定岷当归药材中的水分、总灰分、酸不溶灰分、浸出物、挥发油、阿魏酸，分析岷县土壤中无机元素与岷当归药材质量的相关性。 结果岷县不同区域岷当归药材各理化指标没有明显差异，岷当归药材中浸出物、挥发油、阿魏酸含量测定值均高于2015版《中华人民共和国药典》当归标准，岷当归药材中Na、Cu、V、Co、Se、Mo、U无机元素对岷当归药材理化检测指标影响较显著，土壤中Na、K、Fe、Al、V、Ni、Cu、As、Mo、Ag、Sb、Ti无机元素对岷当归药材理化检测指标影响较显著。岷当归药材中重金属Pb、Cd、As、Hg、Gu均未超过国家规定，其中Hg在各批次岷当归药材及种植土壤中均未检出。 结论岷县区域内所产当归质量均高于药典标准，符合道地药材属性。
Abstract:
ObjectiveTo build the method of determining the elements in Mindanggui (Danggui produced in Minxian county) by ICP-MS, and analyze the influence of inorganic elements contained in the soil of Mindanggui plantation on the quality of Mindanggui. MethodsICP-MS was used to detect the contents of inorganic elements in plantation soil and 20 batches of Mindanggui from different producing areas of Minxian county, measure the moisture, total ash, acid insoluble ash, extract, volatile oil and ferulic acid in Mindanggui, survey the connections between inorganic elements in soil and the quality of Mindanggui. ResultsNo obvious difference was found in physicochemical parameters of Mindanggui from different regions of Minxian county, the measured values of extract, volatile oil, ferulic acid of Mindanggui were higher than the criteria of Danggui in 2015 edition of Chinese Pharmacopoeia, inorganic elements including Na, Cu, V, Co, Se, Mo and U contained in Mindanggui showed significant influence on physicochemical parameters of Mindanggui, inorganic elements including Na, K, Fe, AI, V, Ni, Cu, As, Sb, Ti and others contained in the soil had significant impact on physicochemical parameters of Mindanggui. None of heavy metals Pb, Cd, As, Hg and Cu contained in Mindanggui exceeded national regulations, among them, Hg was not detected in different batches of Mindanggui and planting soil. ConclusionThe quality of Danggui produced in Minxian regions are higher than Pharmacopoeia standard, and conforms to the attributes of genuine medicinal materials.

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备注/Memo

备注/Memo:
张平（1983—），男，副主任中药师。研究方向：中药及民族药质量标准研究。国家中药材及饮片质量控制重点实验室项目（2020GSMPA-KL06-2）；甘肃省食品药品科研项目（2018GSFDA008）；甘肃省科技重大专项（17ZD2FA009）。
更新日期/Last Update: 2022-08-09