[1]谢小玲,黄适,何锦轶,等.基于中医病因学说探讨HMGB1与IBS-D的相关性[J].西部中医药,2023,36(05):112-115.[doi:10.12174/j.issn.2096-9600.2023.05.26]
　XIE Xiaoling,HUANG Shi,HE Jinyi,et al.The Correlation between HMGB1 and IBS-D from the Etiology of TCM[J].Western Journal of Traditional Chinese Medicine,2023,36(05):112-115.[doi:10.12174/j.issn.2096-9600.2023.05.26]
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基于中医病因学说探讨HMGB1与IBS-D的相关性
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年05期
页码:
112-115
栏目:
出版日期:
2023-05-15

文章信息/Info

Title:
The Correlation between HMGB1 and IBS-D from the Etiology of TCM
作者:
谢小玲1, 黄适2, 何锦轶1, 王凯1, 覃川峰1, 龚纯1
1.广西中医药大学，广西 南宁 530001
2.广西中医药大学附属瑞康医院，广西 南宁 530011
Author(s):
XIE Xiaoling1, HUANG Shi2, HE Jinyi1, WANG Kai1, QIN Chuanfeng1, GONG Chun1
1.Guangxi University of Chinese Medicine, Nanning 530001, China
2.Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China
关键词:
肠易激综合征; 腹泻型; 高迁移率族蛋白B1; 中医病因学说
Keywords:
irritable bowel disease;  diarrhea predominant; HMGB1; the etiology of TCM
分类号:
R256.34
DOI:
10.12174/j.issn.2096-9600.2023.05.26
文献标志码:
B
摘要:
基于中医病因学说探讨高迁移率族蛋白B1（high-mobility group box-1，HMGB1）与腹泻型肠易激综合征（diarrhea predominant-irritable bowel syndrome，IBS-D）的相关性，指出IBS-D中医病因主要涉及外感、饮食、情志、脏腑虚损等方面，病机为五脏功能失调及气机逆乱；HMGB1是参与炎症反应和免疫机制的重要因子，与外感、饮食、情志、脏腑虚损等致病因素有一定联系，因此可从HMGB1角度研究IBS-D，以扩展IBS-D的研究范围。
Abstract:
The paper discusses the correlation between HMGB1 and IBS-D based on the etiology of TCM, TCM causes of IBS-D mainly involve external factors, diet, emotion and visceral deficiency, and the pathogenesis belong to the dysfunction of five viscera and Qi movement disturbance; HMGB1 is the important factors involved in inflammatory reaction and immune mechanism, related to pathogenic factors such as external factors, diet, emotion and visceral deficiency to a certain degree, hence, IBS-D could be studied from the angle of HMGB1, so as to expand the scope of IBS-D.

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备注/Memo

备注/Memo:
谢小玲（1993—），女，硕士学位。研究方向：消化系统疾病的中西医结合诊治。国家自然科学基金地区基金（81560754）；广西中医药大学校级创新项目（YCSY201900110）。
更新日期/Last Update: 2023-05-15