[1]王鼎盛,赵天莹,何琼,等.基于中医传承辅助平台对布鲁氏菌病肝肾亏虚证用药规律的分析[J].西部中医药,2024,37(06):84-88.[doi:10.12174/j.issn.2096-9600.2024.06.20]
　WANG Dingsheng,ZHAO Tianying,HE Qiong,et al.The Medication Rules of Liver-kidney Depletion Pattern Brucellosis Based on TCMISS[J].Western Journal of Traditional Chinese Medicine,2024,37(06):84-88.[doi:10.12174/j.issn.2096-9600.2024.06.20]
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基于中医传承辅助平台对布鲁氏菌病肝肾亏虚证用药规律的分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年06期
页码:
84-88
栏目:
二次研究
出版日期:
2024-06-15

文章信息/Info

Title:
The Medication Rules of Liver-kidney Depletion Pattern Brucellosis Based on TCMISS
作者:
王鼎盛1, 赵天莹1, 何琼1, 席进孝1, 王小荣2, 关宏1, 周晓艳1, 赵琦1
1.甘肃省疾病预防控制中心,甘肃 兰州 730000
2.甘肃中医药大学，甘肃 兰州 730000
Author(s):
WANG Dingsheng1, ZHAO Tianying1, HE Qiong1, XI Jinxiao1, WANG Xiaorong2, GUAN Hong1, ZHOU Xiaoyan1, ZHAO Qi1
1.Gansu Center for Disease Control and Prevention, Lanzhou 730000, China
2.Gansu University of Chinese Medicine, Lanzhou 730000, China
关键词:
布鲁氏菌病; 肝肾亏虚证; 中医传承辅助系统; 数据挖掘; 用药规律
Keywords:
brucellosis; liver-kidney depletion pattern; TCMISS; data mining; medication rules
分类号:
R378.5
DOI:
10.12174/j.issn.2096-9600.2024.06.20
文献标志码:
A
摘要:
目的分析中医治疗布鲁氏菌病肝肾亏虚证的用药规律，挖掘有效的药物组合及新处方。 方法检索相关数据库并查阅资料，收集关于布鲁氏菌病肝肾亏虚证的文献和医案，筛选治疗该病证的方剂。基于中医传承辅助平台（V2.5）建立方药特征数据库，并通过关联规则分析法、熵层次聚类等方法，对处方用药进行数据分析，包括对用药频次统计、组方规律进行挖掘等。 结果肝肾亏虚的症状出现54条，症状频次总共224次，其中频率在5以上的18条，总共出
Abstract:
ObjectiveTo unearth the effective drug combination and new prescription by analyzing the medication laws of TCM therapy for liver-kidney depletion pattern brucellosis. MethodsThe literature and medical cases of liver-kidney depletion pattern brucellosis were collected by searching the relevant database and checking the data, to screen the prescriptions of treating the disease. The database of prescription and drugs was established based on TCMISS V2.5, the data of the prescribed herbs, including medication frequency statistics, the rule of the prescriptions, was analyzed through association rule analysis method, entropy hierarchical clustering. ResultsThere were 54 symptoms of liver and kidney deficiency, and the frequency of symptoms was 224 times in total, of which 18 symptoms occurred more than five times, 147 times in total, accounting for 65.6% of the total. All 17 prescriptions and 38 herbs were selected, the most frequently used herbs were Niuxi (achyranthis bidentatae radix), Gouqizi (lycii fructus), Danggui (angelicae sinensis radix), Xuduan (dipsaci radix) and Sangjisheng (taxilli herba), 14 core drug combinations were obtained, the medication rule were mainly the compatibility between Niuxi, Dangshen (Codonopsis radix), Xuduan, Danggui, Sangjisheng, Gouqizi and Huangjing (polygonati rhizoma). four core combinations and two new prescriptions were gained. ConclusionLiver-kidney depletion pattern brucellosis principally adopts the drugs of tonifying liver and kidney, strengthening the bones and muscles, relieving rheumatism, nourishing Qi and blood, the new prescription could reflect the thinking of eliminating the pathogen and enhancing healthy Qi, treating the symptoms and the root causes, strengthening the liver and kidney, eliminating rheumatism to enrich Qi and blood, heal the arthralgia.

相似文献/References:

[1]杨宏伟.中药口服、塌渍联合西药治疗布鲁氏菌病疗效观察[J].西部中医药,2022,35(05):144.[doi:10.12174/j.issn.2096-9600.2022.05.33]
　YANG Hongwei.Clinical Observation on Oral Administration of Herbs, Hot Compressing with Herbs Combined with Western Medicine in the Treatment of Brucellosis[J].Western Journal of Traditional Chinese Medicine,2022,35(06):144.[doi:10.12174/j.issn.2096-9600.2022.05.33]
[2]王鼎盛,赵天莹,何琼,等.基于中医传承辅助平台分析布鲁氏菌病瘀血阻络证的用药规律[J].西部中医药,2023,36(08):59.[doi:10.12174/j.issn.2096-9600.2023.08.15]
　WANG Dingsheng,ZHAO Tianying,HE Qiong,et al.The Medication Rules of Blood Stasis Obstructing Collateral Pattern Brucellosis Based on TCMISS[J].Western Journal of Traditional Chinese Medicine,2023,36(06):59.[doi:10.12174/j.issn.2096-9600.2023.08.15]

备注/Memo

备注/Memo:
王鼎盛（1975—），男，硕士学位，主任医师。研究方向：布鲁氏菌病的防治与研究。E-mail：744369107@qq.com。2019年甘肃省中医药科研课题（GZK-2019-58）。
更新日期/Last Update: 2024-06-15