[1]刘猛,高家荣,魏良兵.多指标综合评分法优选参术调脾颗粒方中白术和陈皮的醇提取工艺[J].西部中医药,2024,37(07):5-9.[doi:10.12174/j.issn.2096-9600.2024.07.02]
　LIU Meng,GAO Jiarong,WEI Liangbing.Optimization of Alcohol Extraction Process of Baizhu and Chenpi in Shenzhu Spleen-adjusting Granules by Multi-index Comprehensive Scoring Method[J].Western Journal of Traditional Chinese Medicine,2024,37(07):5-9.[doi:10.12174/j.issn.2096-9600.2024.07.02]
点击复制

多指标综合评分法优选参术调脾颗粒方中白术和陈皮的醇提取工艺
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年07期
页码:
5-9
栏目:
质量分析
出版日期:
2024-07-15

文章信息/Info

Title:
Optimization of Alcohol Extraction Process of Baizhu and Chenpi in Shenzhu Spleen-adjusting Granules by Multi-index Comprehensive Scoring Method
作者:
刘猛1, 高家荣2, 魏良兵2
1.皖西卫生职业学院附属医院，安徽 六安 237008
2.安徽中医药大学第一附属医院，安徽 合肥 230031
Author(s):
LIU Meng1, GAO Jiarong2, WEI Liangbing2
1.Affiliated Hospital of West Anhui Health Vocational College, Lu'an 237008, China
2.The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China
关键词:
参术调脾颗粒; 提取工艺; 白术内酯Ⅰ; 白术内酯Ⅲ; 多指标综合评分法
Keywords:
spleen-adjusting granules; extraction process; atractylenolide Ⅰ; atractylenolide Ⅲ; multi-index comprehensive scoring method
分类号:
R283
DOI:
10.12174/j.issn.2096-9600.2024.07.02
文献标志码:
A
摘要:
目的优选参术调脾颗粒方中白术和陈皮的最佳醇提取工艺。 方法以参术调脾颗粒中醇溶性浸出物、白术内酯Ⅰ和白术内酯Ⅲ的含量为醇提取工艺的考察指标，通过多指标综合评分法考察不同因素和水平对提取工艺的影响。 结果参术调脾颗粒方中白术和陈皮最佳醇提取工艺为A1B3C2D3，即乙醇浓度65%，加10倍量乙醇，每次提取1.5 h，提取3次。 结论优选的参术调脾颗粒方中白术和陈皮醇提取工艺合理可行，有效成分提取效率高。
Abstract:
ObjectiveTo optimize the best alcohol extraction process of Baizhu (Atractylodis macroce-phalae rhizoma) and Chenpi (Citri reticulatae pericarpium) in Shenzhu spleen-adjusting granules. MethodsThe contents of alcohol soluble extract, atractylolideⅠand atractylolide Ⅲ in Shenzhu spleen-adjusting granules were used as the indexes of alcohol extraction process, and the influences of different factors and their levels on extraction process were investigated using multi-index comprehensive scoring method. ResultsThe best alcohol extraction process of Baizhu and Chenpi from the granules was A1B3C2D3, that is, ethanol concentrations 65%, adding ten times amount of ethanol, extracting for 1.5 h each time, three times. ConclusionThe optimized alcohol extraction process of Baizhu and Chenpi from Shenzhu spleen-adjusting granules is rational and feasible with high extraction efficiency of active ingredients.

相似文献/References:

[1]梁海宁,沈涛,陈二林,等.正交试验优选萆清栓的提取工艺*[J].西部中医药,2012,25(12):20.
　LIANG Hai-ning,SHEN Tao,CHEN Er-lin,et al.Extraction Process of BiQing Suppository Optimized with Orthogonal Design[J].Western Journal of Traditional Chinese Medicine,2012,25(07):20.
[2]罗西湘,马潇△,宋平顺.复方甘肃丹参滴丸提取工艺研究*[J].西部中医药,2012,25(11):39.
　LUO Xi-xiang,MA Xiao,SONG Ping-shun.Study on Extraction Process of Compound Gansu DanShen Dripping Pills[J].Western Journal of Traditional Chinese Medicine,2012,25(07):39.
[3]郭敏,王晓琳,黄聪琳,等.镰形棘豆总黄酮提取工艺的比较研究*[J].西部中医药,2014,27(02):34.
　GUO Min,WANG Xiaolin,HUANG Conglin,et al.Comparative Study on the Extraction Processes of Total Flavonoids from LianXing JiDou[J].Western Journal of Traditional Chinese Medicine,2014,27(07):34.
[4]卢利军.金芪利水排石颗粒的水提取工艺研究[J].西部中医药,2014,27(03):48.
　LU Lijun.Water Extraction Technology of JinQi LiShui PaiShi Granules[J].Western Journal of Traditional Chinese Medicine,2014,27(07):48.
[5]刘光斌,毛和平,谢六生,等.金锁二仙口服液的提取纯化工艺优选[J].西部中医药,2015,28(03):37.
[6]李广雷,杨薇,林青华,等.枸杞子的提取工艺研究[J].西部中医药,2015,28(08):18.
[7]李 强,李庆超,周长征△.L16(45)正交实验优化黄刺玫花黄酮物质提取工艺[J].西部中医药,2015,28(10):59.
[8]李军山,陈钟,高晗,等.麦冬提取工艺近红外光谱与液相色谱比较研究[J].西部中医药,2017,30(01):20.
　Study on MaiDong Extraction Technology of Near-infrared Spectroscopy and Liquid Chromatography.Study on MaiDong Extraction Technology of Near-infrared Spectroscopy and Liquid Chromatography[J].Western Journal of Traditional Chinese Medicine,2017,30(07):20.
[9]王东东,孙芸,周光△.正交实验法优选华佗麻药加减方乳膏剂提取工艺的研究[J].西部中医药,2017,30(02):28.
　WANG Dongdong,SUN Yun,et al.Study on Extraction Methods of Huatuo Anesthetic Recipe Modified Cream Selected by Orthogonal Design[J].Western Journal of Traditional Chinese Medicine,2017,30(07):28.
[10]赵妮,邓毅△,刘靓,等.正交实验优选甘草总黄酮和总皂苷提取工艺[J].西部中医药,2016,29(02):34.
　ZHAO Ni,DENG Yi,LIU Liang,et al.Optimization of Extraction Technology of Total Flavonoids and Total Saponins from GanCao by Orthogonal Test[J].Western Journal of Traditional Chinese Medicine,2016,29(07):34.

备注/Memo

备注/Memo:
刘猛（1986—），男，硕士学位，副主任药师。研究方向：中药制剂研究与开发、临床药学。国家自然科学基金（81603574）。
更新日期/Last Update: 2024-07-15